نتایج جستجو برای: snp309

تعداد نتایج: 201  

2009
Giuseppe Toffoli Paola Biason Antonio Russo Elena De Mattia Erika Cecchin Claudia Maria Hattinger Michela Pasello Marco Alberghini Cristina Ferrari Katia Scotlandi Piero Picci Massimo Serra

Purpose: The germ-line polymorphisms TP53 Arg72Pro and MDM2 SNP309 T>G are risk factors for tumor development and affect response to chemotherapy and survival in several cancers, but their prognostic and predictive value in patients with high-grade osteosarcomas is not yet defined. The purpose of this study was to investigate the effect of the TP53 Arg72Pro and the MDM2 SNP309 on the risk of os...

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