OBJECTIVES The use of chitosan nanoparticles (CNPs) in endodontics is of interest due to their antibiofilm properties. This study was to investigate the ability of bioactive CNPs to remove the smear layer and inhibit bacterial recolonization on dentin. MATERIALS AND METHODS One hundred bovine dentin sections were divided into five groups (n = 20 per group) according to the treatment. The irri...

Objectives. To evaluate and compare the antifungal efficacy of 1.3% NaOCl/MTAD with 2.5% sodium hypochlorite (NaOCl), 2% chlorhexidine gluconate (CHX), and iodine potassium iodide (IKI). Materials and Methods. Fifty-two single rooted teeth were used which were divided into four groups with 10 teeth in each group: 2.5% NaOCl, 2% CHX, IKI, 1.3% NaOCl/MTAD, and physiologic saline. Two teeth served...

INTRODUCTION The purpose of this study was to evaluate the effects of different solutions used for final irrigation on sealer penetration into dentinal tubules. METHODS Thirty-two recently extracted human mandibular premolar teeth were treated with sodium hypochlorite (NaOCl) irrigation. The samples were divided into 4 groups according to the final irrigation solution used: (1) the EDTA group...

Introduction: Endocyn, a super-oxidized water-based irrigation solution, has been reported to be non-toxic against mammalian cells, yet highly efficacious against bacteria; however, its effect against fungi and fungal biofilms remain unknown. This study evaluated the antifungal efficacy of Endocyn compared to sodium hypochlorite (NaOCl) and chlorhexidine (CHX). Methods: An in vitro biofilm syst...

Final root canal irrigation stands as an effective strategy for eliminating the dentin infection. This study aimed to investigate and compare the antibacterial efficacy of QMix and other four final irrigation regimens in reducing Enterococcus faecalis within human root canals. Single-canal human teeth contaminated with E. faecalis for 4 weeks were prepared chemomechanically with sodium hypochlo...

background: interaction between local anesthetic solution, lidocaine hydrochloride (with and without adrenaline), and root canal irrigants such as sodium hypochlorite (naocl), ethylene diamine tetra-acetic acid (edta), and chlorhexidine (chx) has not been studied earlier. hence, the purpose of this in vitro study was to evaluate the chemical interaction between 2% lidocaine hydrochloride (with ...

To prevent disease transmission, 0.05% chlorine solution is commonly recommended for handwashing in Ebola Treatment Units. In the 2014 West Africa outbreak this recommendation was widely extended to community settings, although many organizations recommend soap and hand sanitizer over chlorine. To evaluate skin irritation caused by frequent handwashing that may increase transmission risk in Ebo...

BACKGROUND The success of endodontic treatment depends on a few crucial factors. One of these factors is the complete chemomechanic preparation of root canal against various bacteria. In particular, the effect of resistant bacteria may cause intense pain with flare-up and formation of periapical lesions. Therefore, the strong effect of irrigants plays an important role in terms of the complete ...

The aim of this study was to compare the influence a final rinse with and without passive ultrasonic irrigation (PUI), using 17% ethylenediaminetetraacetic acid (EDTA) or 10% citric (CA), 2.5% sodium hypochlorite (NaOCl) PUI, on sealing ability root canal fillings. Root instrumentation performed in single-rooted premolars NaOCl as irrigant. Subsequently, roots were randomly allocated into four ...