نتایج جستجو برای: solid lipid nanoparticle
تعداد نتایج: 375951 فیلتر نتایج به سال:
The loading and containment of cargo within nanoparticles and their efficient delivery to cells represent a primary challenge in nanomedicine. We report lipid exchange between free and mesoporous silica nanoparticle-supported lipid bilayers as an effective means of containing cargo, controlling charge, and directing delivery to mammalian cells. The delivery of a membrane-impermeable dye (calcei...
Sinapic acid (SA), belonging to the phenylpropanoid family, and its derivatives are secondary metabolites found in plant kingdom. In recent years, they have drawn attention because of their various biological activities, including neuroprotective effects. this study, SA was incorporated into two different nanoparticle systems, solid lipid nanoparticles (SLN) nanostructured carriers (NLC). The i...
BACKGROUND The purpose of this work is to provide experimental evidence on the interactions of suspended nanoparticles with artificial or biological membranes and to assess the possibility of suspended nanoparticles interacting with the lipid component of biological membranes. METHODS 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) lipid vesicles and human red blood cells were incubat...
In this communication, solid-phase reactions for the synthesis of Lys-monofunctionalized gold nanoparticles are described. A controlled and selective fabrication of linear nanoparticle arrays can be achieved through peptide linkage systems, and therefore it is essential to prepare Fmoc amino acid nanoparticle building blocks susceptible to Fmoc solid-phase peptide synthesis. Gold nanoparticles ...
Thyrotropin or thyroid-stimulating hormone (TSH) is used as a marker for thyroid function. More precise and more sensitive immunoassays are needed to facilitate continuous monitoring of thyroid dysfunctions and to assess the efficacy of the selected therapy and dosage of medication. Moreover, most thyroid diseases are autoimmune diseases making TSH assays very prone to immunoassay interferences...
Aim: A successful gene therapy requires a delivery system for overcoming various biological barriers. For this, we adapted the factorial design and response surface methodology to cationic solid lipid nanoparticle production process. Methods: Screening optimization of formulations were carried out with 3 factors levels using Box-Behnken Design. Then, nanoparticles physicochemically characteriz...
The engineering of responsive multifunctional delivery systems that combine therapeutic and diagnostic (theranostic) capabilities holds great promise and interest. We describe the design of thermosensitive liposome-nanoparticle (NP) hybrids that can modulate drug release in response to external heating stimulus. These hybrid systems were successfully engineered by the incorporation of gold, sil...
Heat transfer phenomena of flat plate solar collector filled with different nanofluids has been investigated numerically. Galerkin’s Finite Element Method is used to solve the problem. Heat transfer rate, average bulk temperature, average sub-domain velocity, outlet temperature, thermal efficiency, mean entropy generation and Bejan number has been investigated by varying the solid nanoparticle ...
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