This research aims to know the implementation of learning model and effect performance guided inquiry collaborative on students' achievement solubility product concepts. study used design experiments was conducted in 11th grade at Malang High School group's pretest post-test design. Data were collected using a multiple-choice test analyzed descriptive inferential statistics (t-test). Student wo...

The absorption of poorly water-soluble drugs is influenced by the luminal gastrointestinal fluid content and composition, which control solubility. Simulated intestinal fluids have been introduced into dissolution testing including endogenous amphiphiles and digested lipids at physiological levels; however, in vivo individual variation exists in the concentrations of these components, which wil...

The purpose of this study was to evaluate the incompatibility of ceftriaxone sodium with calcium-containing products using the ionic product of precipitation, and the measurement of insoluble microparticles using a light obscuration particle counter. Appropriate volumes of 2% (w/v) calcium chloride solution were added to 0.4-2 mg/ml ceftriaxone isotonic sodium chloride solution, to make solutio...

About 30% of drug candidate molecules are rejected due to pharmacokinetic-related failures. When poor pharmaceutical properties are discovered in development, the costs of bringing a potent but poorly absorbable molecule to a product stage by "formulation" can become very high. Fast and reliable in vitro prediction strategies are needed to filter out problematic molecules at the earliest stages...

In the present study, the behavior of the different isotopes activity concentrations for three different rock samples (siltstone, shale and sandy dolomite) as well as in the different leachates of these rocks were studied at different time intervals, using a HP-Ge spectrometer. The activity concentration of U for the leachates gradually increases while that for U is nearly constant. The results...

the solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. fused dispersions (fds) of simvastatin (sim) using peo-ppo block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. the accumulative solub...

Considering the health benefits of extruding germinated multi-millet grains, current study emphasizes extrusion processing grain blends (sorghum millet, finger foxtail pearl and rice) in various ratios 11.5:11.5:11.5:11.5:6:4 to produce nutritionally important expanded snack products. The process was adjusted for all preparations under a controlled moisture content 20-21% (w.b.), at most stable...