In this paper, the performance of nanofiltration membrane process in removing Pb(II) from aqueous solution was modeled by the pore flow-concentration polarization model. The model was fabricated based on the simultaneous resolving of Extended Nernst–Planck equation(ENP), film theory, and osmotic pressure model. The effects of various operational parameters such as the applied pressure, feed con...

In this work, several machine learning techniques are presented for nanofiltration modeling. According to the results, specific errors are defined. The rejection due to Nanofiltration increases with pressure but decreases with increasing the concentration of chloride ion. Methods of machine learning represent the rejection of nanofiltration as a function of concentration, pH, pressure and also ...

The performance of a nanofiltration membrane for the removal of the nickel ion was studied as a function of the nickel concentration, solution pH, and the background ionic strength of the solution. Nanofiltration is investigated as a means to determine to what extent the nickel ions could be removed from acid mine drainage; thus the effect of solution chemistry on nanofiltration performance is ...

The control of impurities is a critical issue in pharmaceutical industry and very strict regulations related with this issue have been introduced by ICH (International Conference on Harmonisation). The drugs impurities in general are classified into two types: (1) impurities associated with the Active Pharmaceutical Ingredients (API) production and, (2) impurities generated during formulation a...

Due to the discovery of RNAi, oligonucleotides (oligos) have re-emerged as a major pharmaceutical target that may soon be required in ton quantities. However, it is questionable whether solid-phase oligo synthesis (SPOS) methods can provide a scalable synthesis. Liquid-phase oligo synthesis (LPOS) is intrinsically scalable and amenable to standard industrial batch synthesis techniques. However,...

In this work, cellulose acetate (CA) nanofiltration (NF) membranes were prepared via non-solvent phase inversion technique (NIPS). Polymer concentration was varied from 22 to 25 wt% in order to study its effect on the membrane properties. The fabricated membranes were characterized in terms of morphological analysis using scanning electron microscopy (SEM), contact angle, water content, water p...