نتایج جستجو برای: somatic antigen
تعداد نتایج: 241525 فیلتر نتایج به سال:
In this study, we performed fliC PCR-restriction fragment length polymorphism (RFLP) to investigate whether this technique would be better than classic serotyping for the characterization of the H antigen in enterotoxigenic Escherichia coli (ETEC) strains. We showed that the fliC genes from ETEC strains can be characterized by restriction analysis of their polymorphism. Only one allele of the f...
background: the present study deals with the effect of helminthic infection as nematode parasite like aspiculuris tetraptera on the haematological parameters of infected and vaccinated mice. methods: totally 15 mice were used. five mice were used for positive control, 5 mice used for negative control and 5 mice used for experiment. the hematological parameters were studied viz. rbc, hb, and se...
Expression of surface immunoglobulin appears critical for the growth and survival of B-cell lymphomas. In follicular lymphoma, we found previously that the Ig variable (V) regions in the B-cell receptor express a strikingly high incidence of N-glycosylation sequons, NX(S/T). These potential glycosylation sites are introduced by somatic mutation and are lymphoma-specific, pointing to their invol...
Phase I and Phase II Sh. sonnei exhibit differences in their susceptibility to the T series of bacteriophages. Both microorganisms are lysed by T(2) and T(6), but only the Phase II bacillus is lysed by T(3), T(4), and T(7). Lysis of the Phase I or Phase II bacillus by T(2) or T(6) is not inhibited by the homologous type-specific antigen. In the presence of an appropriate cofactor, however, the ...
Shigella sonnei, an intestinal pathogen, produces a characteristic form I cell surface antigen now known to be plasmid encoded. We considered that the GalE Salmonella typhi Ty21a oral vaccine strain, highly effective against typhoid, might be modified so as to be protective also against shigellosis due to S. sonnei. The plasmid responsible for form I antigen synthesis was therefore conjugally t...
Affinity maturation of antibodies during immune responses is achieved by multiple rounds of somatic hypermutation and subsequent preferential selection of those B cells that express B cell receptors with improved binding characteristics for the antigen. The mechanism underlying B cell selection has not yet been defined. By employing an agent-based model, we show that for physiologically reasona...
We have studied 19 S107 heavy chain variable region gene (VH11)-encoded monoclonal antibodies from NZBWF1 mice. These studies show that a single VH gene can encode both antibodies to foreign antigens (anti-phosphorylcholine) and to self antigens (anti-double-stranded DNA) in the same animal. All of the anti-DNA antibodies contain many somatic mutations compared with the relevant germline genes....
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