Introduction: Production of extended-spectrum beta-lactamase enzymes (ESBLs) in E. coli creates many problems for patients. These enzymes are located on transferable elements and can hydrolyze penicillins, broad-spectrum cephalosporins, and aztreonam. This study aimed to determine the clinical isolates of E. coli producing ESBLs of blaSHV and blaTEM in the city of Zanjan. Methods: This cross...

Biological functions of antibiotics are not limited to killing. The most likely function of antibiotics in natural microbial ecosystems is signaling. Does this signaling function of antibiotics also extend to the eukaryotic - in particular mammalian - cells? In this review, the host modulating properties of three classes of antibiotics (macrolides, tetracyclines, and β-lactams) will be briefly ...

conclusions this study showed that multiple β-lactamases can be produced in burn isolates. this suggests that use of cephalosporins and carbapenems should be restricted in burn isolates to minimize the development and spread of these multidrug resistant pathogens. results there was 99% resistance to carbenicillin, and ticarcillin, 98% to cotrimoxazole, 96% to ciprofloxacin, and aztreonam, 95% t...

The present study investigated the clinical effect of antibiotic de-escalation therapy in elderly patients with chronic obstructive pulmonary disease (COPD) complicated with severe pneumonia. According to the parity method of hospitalization number, 86 cases were selected and divided into the observation and control group with 43 cases each. Based on empirical antibiotic application, levofloxac...

Introduction: Stenotrophomonas maltophilia is a nosocomial multi drug resistant opportunistic pathogen which causes infections in vulnerable patients with cancer, cystic fibrosis and indwelling catheters. Methods: 45 clinical S. maltophilia isolates were collected from blood samples and identified by biochemical tests. Susceptibility to different antibiotics including co-trimoxazole, levofloxac...

(1) Dear Alice, I heard that while it's generally not advised to take antibiotics while on the birth control pill, it's still okay to take tetracycline. Is this true? (2) Dear Alice, I have heard many many times that antibiotics interfere with the effectiveness of oral contraceptives, but what about the depo-provera shot? Is there any research showing decreased effectiveness of Depo-Provera whe...

(1) Dear Alice, I heard that while it's generally not advised to take antibiotics while on the birth control pill, it's still okay to take tetracycline. Is this true? (2) Dear Alice, I have heard many many times that antibiotics interfere with the effectiveness of oral contraceptives, but what about the depo-provera shot? Is there any research showing decreased effectiveness of Depo-Provera whe...

(1) Dear Alice, I heard that while it's generally not advised to take antibiotics while on the birth control pill, it's still okay to take tetracycline. Is this true? (2) Dear Alice, I have heard many many times that antibiotics interfere with the effectiveness of oral contraceptives, but what about the depo-provera shot? Is there any research showing decreased effectiveness of Depo-Provera whe...

(1) Dear Alice, I heard that while it's generally not advised to take antibiotics while on the birth control pill, it's still okay to take tetracycline. Is this true? (2) Dear Alice, I have heard many many times that antibiotics interfere with the effectiveness of oral contraceptives, but what about the depo-provera shot? Is there any research showing decreased effectiveness of Depo-Provera whe...

(1) Dear Alice, I heard that while it's generally not advised to take antibiotics while on the birth control pill, it's still okay to take tetracycline. Is this true? (2) Dear Alice, I have heard many many times that antibiotics interfere with the effectiveness of oral contraceptives, but what about the depo-provera shot? Is there any research showing decreased effectiveness of Depo-Provera whe...