Spotlight on Cancer Informatics is a new feature of Cancer Informatics designed to help build a sense of community among informatics researchers attempting to at once provide informatics services to cancer studies while simultaneously conducting independent research that leads to advances in informatics solution. Individuals are “Spotlighted” at the invitation of the Editor-in-Chief. To be cons...

The 35-year-old Minnesota woman’s winter vacation in the neighboring state of Wisconsin was going great, until her ski snapped and the accident happened. Breaking several bones, suffering internal bleeding, and rendered unconscious, the woman needed immediate and acute medical attention the second she was wheeled into a nearby hospital. What the physicians there didn’t know was this woman had a...

Can cloud cover on Election Day be used to predict the next governor? What can college football games tell us about the next presidential race? These are questions that motivate Fred Wolens, a junior in the Political Science department, in his ongoing research on Retrospective Voter Theory. Retrospective Voter Theory assumes that voters will choose to re-elect—or not to re-elect—an incumbent ba...

H umanoid robotics is an emerging and challenging research field that has received significant attention during the past years and will continue to play a central role in robotics research and many applications of the 21st century. Regardless of the application area, one of the common problems dealt with in humanoid robotics is the understanding of humanlike information processing and the under...

Delivery of cytotoxic agents specifically to malignant cells has always been a goal of cancer therapy. With the development of monoclonal antibodies for clinical use, this goal has become a reality, and antibody-drug conjugates are now part of standard therapy in diseases such as lymphoma and breast cancer. Brentuximab vedotin, which targets CD30, has contributed to the success of antibody-drug...

Remarkably few hormones have been identified that stimulate appetite. The recent discovery of asprosin, a hormone that activates AgRP neurons to increase food intake and body weight, begins to fill this gap (Duerrschmid et al., 2017; Romere et al., 2016).

© 1999 Canadian Medical Association or its licensors Technology: Intraoperative MRI Use: This mobile, 1.5 Tesla MRI system is placed into a standard neurosurgical operating room. It is used to plan accurate surgical corridors, confirm the accomplishment of operative objectives and detect acute complications such as hemorrhage and ischemia. History: Lesion localization is paramount for safe neur...

Ionic liquids are an emerging class of materials with a diverse and extraordinary set of properties. Understanding the origins of these properties and how they can be controlled by design to serve valuable practical applications presents a wide array of challenges and opportunities to the chemical physics and physical chemistry community. We highlight here some of the significant progress alrea...

Technology: Sonohysterography Use: With this technique, a refinement of transvaginal ultrasound imaging, saline is infused into the uterine cavity to enhance the imaging of the endometrium. The procedure was initiated because of the low sensitivity and specificity of transvaginal ultrasound for detecting endometrial pathology. In addition, the cost, inconvenience and radiation exposure associat...

This spotlight review focuses on the second-generation proteasome inhibitor carfilzomib, which was recently approved by the US Food and Drug Administration for treatment of relapsed and refractory multiple myeloma patients who have received at least 2 prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of the comple...