Despite significant progress, new therapeutic approaches for advanced non-small cell lung cancer (NSCLC) are highly needed, particularly for the treatment of patients with squamous cell carcinoma. The epidermal growth factor receptor (EGFR) is often overexpressed in NSCLC and represents a relevant target for specific treatments. Although EGFR mutations are more frequent in non-squamous histolog...

Yonelinas et al. (2002) found that hypoxic patients exhibited deficits in recollection that left familiarity relatively unaffected. In contrast, Manns, Hopkins, Reed, Kitchener, and Squire (2003) studied a group of hypoxic patients who suffered severe and equivalent deficits in recollection and familiarity. We reexamine those studies and argue that the discrepancy in results is likely due to di...

Multiple sclerosis (MS) and migraine are two common neurological disorders affecting women more than men. Sleep quality impairment has been reported in both diseases. The goal of this study was to compare sleep quality and depression between women with MS and migraine. Seventy women with migraine and 75 women with MS were enrolled in this study. Participants were asked to fill-out valid and rel...

PURPOSE The aim of this study is to examine the association between the distribution of ACTN3 genotypes and alleles in power, speed, and strength-oriented athletics. METHODS ACTN3 genotyping was carried out for a total of 975 Korean participants: top-level sprinters (n = 58), top-level strength athletes (n = 63), and healthy controls (n = 854). RESULTS Genetic associations were evaluated by...

BACKGROUND SQUIRE demonstrated addition of necitumumab to gemcitabine and cisplatin significantly improved survival in patients with stage IV sq-NSCLC. Here, we report additional outcomes for the subpopulation of patients with tumor epidermal growth factor receptor (EGFR) protein expression. PATIENTS AND METHODS Patients with pathologically confirmed stage IV sq-NSCLC were randomized 1:1 to r...

A long time ago, there was a beautiful girl named " Mariah ". Mariah has a pure beauty like an wonderful smelling flower that can make any man's heart go round and round just concentrically. She has curly golden hair, azure eyes, coral lips and a dimple on her face. She has soft skin like a baby and always is odoriferous. Mariah not only has these about her. Mariah's silky words and her beautif...

Perirhinal cortex is often regarded as part of a medial temporal lobe (MTL) memory system, mediating memory selectively, and having little role in other functions such as perception (e.g., Squire and Zola-Morgan 1991; Buffalo et al. 1998, 1999; Squire et al. 2004). We and others have argued against this idea, suggesting instead that perirhinal cortex may have a role in perception (e.g., Buckley...