BACKgROunD: Acute myocardial infarction is one of the most common presentations of coronary artery disease (CAD). Although coronary angiography remains the gold standard for identification of the infarctrelated artery (IRA), conventional 12-lead electrocardiography (ECG) is an essential tool for diagnosis, risk stratification and prognosis. If specific ECG patterns can be recognized, it will be...

BACKGROUND AND OBJECTIVE In unstable angina, clinical characteristics, resting electrocardiography, and early continuous ST segment monitoring have been individually reported to identify subgroups at increased risk of adverse outcome. It is not known, however, whether continuous ST monitoring provides additional prognostic information in such a setting. DESIGN Observational study of 212 patie...

ST segment deviation is commonly accepted as a sign of myocardial ischemia. Whether indicative of actual myocardial ischemia or not, ST segment changes have been and continue to be generally interpreted as “ischemic ST deviation,” “subendocardial injury,” “coronary insufficiency,” or even “myocardial infarction.” The use of any of these terms intimates coronary artery disease and tends to leave...

OBJECTIVES The purpose of this study was to validate existing 12-lead electrocardiographic (ECG) ST-segment elevation myocardial infarction (STEMI) criteria in the diagnosis of acute myocardial infarction (AMI) and the application of similar ST-segment depression (STEMI-equivalent) criteria with contrast-enhanced cardiac magnetic resonance imaging (ceMRI) as the diagnostic gold standard. BACK...

AIMS To evaluate the prognostic impact of ST depression resolution among patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI in the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. METHODS AND RESULTS In this study, 4729 of 5745 patients had analysable ECGs demonstrating concomitant ST-segment depression. Resolution of summation op...

To assess the exercise-induced changes in repolarization properties in patients with coronary artery disease, we analyzed body surface ECG mapping. The patients studied had a normal resting 12-lead ECG and were divided into 2 groups: group A (n = 15; coronary artery narrowing [–], exercise thallium defect [–], ST depression ≥ 0.1 mV [–]) and group B (n = 17; [+], [+], [+]). All patients in grou...

AIMS To evaluate the prognostic importance of pre-discharge maximal symptom-limited exercise testing (ET) following acute myocardial infarction (AMI) in the era of aggressive reperfusion. METHODS AND RESULTS In the DANAMI-2 (the second DANish trial in AMI) study, patients with ST-elevation AMI (STEMI) were randomized to primary angioplasty (PCI) or fibrinolysis. Of 1462 patients discharged al...

STUDY OBJECTIVES To compare the frequency of daytime and nocturnal cardiac arrhythmias and ST-segment depression episodes among patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), snoring subjects, and healthy subjects, and to analyze the relationship between the cardiac disturbances, sleep characteristics, and sympathetic tone in patients with OSAHS. PATIENTS AND INTERVENTIONS T...

Twenty-six men and women, aged 36-65 years, were studied 8-12 weeks after the first myocardial infarction with regard to silent ischemic ST-segment depression and heart rate by using 24-hour ambulatory electrocardiography and bicycle exercise testing. In 22 patients ambulatory ST-segment recordings revealed 81 episodes of ST-segment depression, including 34 (41.9%) painful and 47 (58.1%) painle...