Background The growing demand for biologicals produced by animal cells motivates the development of more efficient and reliable culture production processes. In the particular case of the industrial production of viral vaccines by Vero cells adhered on microcarriers, the cell propagation phases are mainly devoted to reach high cell density in less time while maintaining a good cell physiologica...

INDIGENOUSNESS IS AN IDENTITY CONSTRUCTED, SHAPED AND LIVED in the politicized context of contemporary colonialism. The communities, clans, nations and tribes we call Indigenous peoples are just that: Indigenous to the lands they inhabit, in contrast to and in contention with the colonial societies and states that have spread out from Europe and other centres of empire. It is this oppositional,...

During vertebrate cardiac development, the heart tube formed by fusion of right and left presumptive cardiac mesoderms (PCMs) undergoes looping toward the right, resulting in an asymmetrical heart. Here, we examined the right and left PCMs with regard to heart-tube looping using right- and left-half newt embryos (Cynops pyrrhogaster ). In the half embryos, the rightward (normal) loop of the hea...

Computational fluid dynamic (CFD) simulation is an effective research approach for understanding velocity fields used in process and equipment intensification. It was found that mixer-settler used in rare earth metal extraction process was unsatisfying in large amount of liquid backlogged, high energy consumption and longtime settling process. In this paper, CFD simulations and experiment valid...

Pollen-tube growth not only represents an essential stage of plant reproduction but also provides an attractive model for studying cell polarity and morphogenesis. For many years, pollen-tube growth has been known to require a tip-focused Ca2+ gradient and dynamic F actin, but the way that these are controlled remained a mystery until recently. Rop appears to be activated at growth sites by a t...

The morphogenesis of the Drosophila embryonic heart tube has emerged as a valuable model system for studying cell migration, cell-cell adhesion and cell shape changes during embryonic development. One of the challenges faced in studying this structure is that the lumen of the heart tube, as well as the membrane features that are crucial to heart tube formation, are difficult to visualize in who...

Twelve of the fourteen isolated components of the luminacin family were assayed for activity to inhibit capillary tube formation in vitro. Seven of them showed potent activity with IC50 values of less than 0.1 microg/ml in a rat aorta matrix culture model. Luminacin D, the strongest inhibitor, inhibited both endothelial cell proliferation and capillary tube formation. Morphological observation ...