Two major dendritic cell (DC) subsets have been described in the pancreas of mice: The CD11c+ CD8α- DCs (strong CD4+ T cell proliferation inducers) and the CD8α+ CD103+ DCs (T cell apoptosis inducers). Here we analyzed the larger subset of CD11c+ CD8α- DCs isolated from the pancreas of pre-diabetic NOD mice for genome-wide gene expression (validated by Q-PCR) to elucidate abnormalities in under...

oxycodone is widely used to alleviate moderate-to severe acute pain, it is an effective analgesic for many types of pain, and is especially useful for paroxysmal spontaneous pain, steady pain, allodynia associated with postherpetic neuralgia, and it is also increasingly used in the management of cancer-related and chronic pain, oxycodone has been found to improve the quality of life of patients...

BACKGROUND The microbial community in a biogas reactor greatly influences the process performance. However, only the effects of deterministic factors (such as temperature and hydraulic retention time (HRT)) on the microbial community and performance have been investigated in biogas reactors. Little is known about the manner in which stochastic factors (for example, stochastic birth, death, colo...

This paper examines the process of transition to turbulence within an accelerating planar liquid jet. By calculating the propagation and spatial evolution of disturbance wave packets generated at a nozzle where the jet emerges, we are able to estimate break–up lengths and break–up times for different magnitudes of acceleration and different liquid to air density ratios. This study uses a basic ...

in this paper, startup performance of upflow anaerobic hybrid reactor and upflow anaerobic sludge blanket reactors in anaerobic treatment of distillery spentwash has been studied under identical conditions of operation. various effluent characteristics like ph, electrical conductivity, chemical oxygen demand, biochemical oxygen demand and total solids and other process parameters like biogas p...

This article concerns the dynamical behavior for a reaction-diffusion equation with integral term. First, by using bifurcation analysis and center manifold theorem, existence of periodic steady-state solution are established special kernel function general respectively. Then, we prove model admits traveling wave solutions connecting this steady state to uniform u=1 applying reduction phase diag...

Probabilistic Boolean Networks have been proposed for estimating the behaviour of dynamical systems as they combine rule-based modelling with uncertainty principles. Inferring PBNs directly from gene data is challenging however, especially when costly to collect and/or noisy, e.g., in case expression profile data. In this paper, we present a reproducible method inferring real measurements taken...

An thermobiological mathematical model is developed to study the recovery of skin tissue ambient temperature after exposure cold till reaches externally applied temperature. This based on Pennes heat balance equation. The Laplace transform method and boundary condition core are used. shows linear dependence steady-state blood perfusion rate. It can be concluded that starts recover above 800 sec...

the simultaneous flow of oil and water in porous media is described by relative permeability curves, mainly derived from laboratory experiments. relative permeability is of paramount importance in predicting reservoir production performance and drive mechanisms and its value depends largely on the volume fraction of fluids present in the test samples. nowadays x-ray scanners are one of the most...

This paper answers some questions about conjugate points along the geodesics corresponding to steady 2D Euler flows, posed by a of Drivas-Misiołek-Shi-Yoneda. We present new sufficient criterion for existence points, which improves on Misiołek. It applies in any rotational cell flow, and case symmetry it captures all known points. give general construction surfaces that admit fluid with given a...