A sterotaxic device for experimental surgery in enucleated eyes is described. This instrument is made entirely of plastic, is inexpensive to make, and has proved to be an invaluable help in teaching microsurgical procedures to ophthalmic residents.

Tremor, both postural and kinetic may be a late complication for victims of severe closed head injury, especially in the young, and may add to their disability. The nature of the tremor is described in eight patients. In each a stereotaxic thalamotomy was performed, dramatically relieving or reducing the severity of tremor in each instance, and resulting in improved function of the affected lim...

SUMMARY In neurophysiology, prior to intracranial recording, it is vital to identify the sites of interest inside the brain and to determine their stereotaxic coordinates in individual brains. This is necessary in order to match sites inside the brain with overlying sites on the skull surface (e.g. to implant devices on the skull) or to overlap functional data arising from neural recordings ont...

Ten patients were studied with computed tomography (CT) in an attempt to determine if CT could be used preoperatively to establish stereotaxic coordinates for an operation and to find out more about how postural changes affect the position of the brain. Certain well defined cerebral structures were chosen as anatomic landmarks, and their relation to the skull determined with the patient in the ...

Stereotaxic subthalamotomy of 55 patients with cerebral palsy gave a good result in 65% of the selected cases. The result was uncertain in 15 and poor in 20%. An independent socio-medical follow-up study confirmed the clinical finding. The more rapid the involuntary movements, the better was the effect of subthalamotomy. Intention tremor was the most suitable symptom for stereotaxic treatment. ...

OBJECTIVE The aim of this study was to investigate voluntary wheel running behavior in the unilateral 6-hydroxydopamine (6-OHDA) rat model. METHODS Male Sprague-Dawley rats were assigned to 2 groups : 6-OHDA group (n=17) and control group (n=8). The unilateral 6-OHDA rat model was induced by injection of 6-OHDA into unilateral medial forebrain bundle using a stereotaxic instrument. Voluntary ...

BACKGROUND The dorsal raphe nucleus (DRN) influences a wide range of behavioral and reward function. In this study, we evaluated electrical stimulation and inactivation of DRN on morphine conditioned place preference (CPP). METHODS The rats were anesthetised (n = 7 for each group) and the electrode and cannula were implanted into the DRN by stereotaxic instrument. Electrical stimulation (100μ...

We have used retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase to examine the origin of thalamic input to the two premotor areas with the densest projections to the motor cortex: the arcuate premotor area (APA) and the supplementary motor area (SMA). Retrograde transport demonstrated that the two premotor areas and the motor cortex each receive thalamic input fr...

In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a Stoelting stereotaxic instrument. A stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. The third ventricular region was infus...