BACKGROUND The clinical management of intravenous immunoglobulin-resistant Kawasaki disease shock syndrome (KDSS) is obscure. CASE CHARACTERISTICS Three children presented with intravenous immunoglobulin-resistant KDSS complicated with myocarditis. OUTCOME All cases were successfully managed with steroid pulse therapy. MESSAGE Steroid pulse therapy is effective in immunoglobulin-resistant...

Nephrotic syndrome is a frequently encountered disease in children. It mostly responsive to high-dose steroids, with some requiring steroid-sparing immunosuppressive regimens, or further, renal biopsy if resistant steroid therapy. However, nephrotic children post-allogeneic bone marrow transplant rarely encountered. The authors report here child who developed for β-thalassaemia major, the suspi...

Plasma lipids were measured in 100 female asthmatic patients receiving long-term steroid therapy. A significant increase in the incidence of endogenous hypertriglyceridaemia but not of hypercholesterolaemia was found. The hypertriglyceridaemia was not due to obesity or diabetes. Neither the dose of steroid, duration of therapy, nor the addition of corticotrophin gel or depot tetracosactrin infl...

introduction: the regulation of neuroendocrine axis is one of the most important goals in the treatment of rheumatoid arthritis. disease modifying drugs such as chloroquine with low dose steroid is the first choice in clinical practice by some physicians. this combination therapy is evaluated by this study. methods: this survey is a prospective study on furty patients. variables for determining...

The treatment of antihistamine and steroid resistant Chronic Idiopathic Urticaria (CIU) during pregnancy poses a challenge due to teratogenicity of immunosuppressants. Omalizumab is a recently FDA approved therapy for CIU and is classified as pregnancy category B. We present an initial series of subjects treated at a tertiary care center for antihistamine and steroid resistant CIU with omalizum...

BACKGROUND/PURPOSE Early reports suggest that the use of steroids after Kasai portoenterostomy may improve bile flow and outcome in infants with biliary atresia. METHODS Of 28 infants with biliary atresia, half received adjuvant high-dose steroids, and half received standard therapy. Infants in the steroid group (n = 14) received intravenous solumedrol (taper of 10, 8, 6, 5, 4, 3, 2 mg/kg/d),...

Background: This paper reports a case of pemphigus vulgaris in middle-aged male with oral lesions and skin eruptions
 Objective: To highlight the complications prolonged steroid therapy.
 Case Report
 A 48-year old presented an eight-month history recurrent mouth ulcers. There was positive cutaneous ulcers on upper extremities, back genital areas. Patient had been placed long ter...

OBJECTIVE To analyze the use of Cyclosporine (CyA) in nephrotic syndrome. METHODS Thirty five children of mean age of 5.9 years with steroid dependent (n = 26) or steroid resistant (n = 9) primary nephrotic syndrome with normal renal functions and who received CyA were studied. CyA was used at a dosage of 6-7 mg/kg/day orally in two divided doses. The mean duration of therapy was 9.6 weeks. A...