Porous and robust 12-connected metal-organic frameworks (MOFs) were constructed by linking tetranuclear lanthanide (Ln) carbonate clusters with organoboron-derived tricarboxylate bridging ligands. The high-connectivity Ln-MOFs feature remarkable thermal and hydrolytic stability and a large number of isolated Lewis acid B(III) and Ln(III) sites on the pore surfaces. The Nd-MOF assisted with sodi...

About the year 1846 Gobley succeeded in obtaining from egg yolk and other organs a substance of a fat-like nature containing nitrogen and phosphorus which he called lecithin [1846]. This substance was soluble in alcohol and in ether, formed an emulsion when rubbed up with water and yielded fatty acids and glycerophosphoric acid on hydrolysis. These observations of Gobley furnished a basis for t...

Neutral oligosaccharides were released by alkaline sodium borohydride reduction of the jelly coating from the South African clawed toad, Xenopus laevis. The oligosaccharides were isolated by HPLC and analyzed by matrix-assisted laser desorption ionization (MALDI)-Fourier transform mass spectrometry (FTMS). The mass spectrometry analysis allowed confirmation of 12 structures first proposed by St...

The development of synthetic methods that afford high yields of the target products with a minimal environmental footprint is a major goal in organic synthesis. The use of carbocatalysts is attractive owing to their low cost and high natural abundance. Carbocatalyts have been applied in the oxidative aromatization and preparation of heteroaromatic compounds such as pyridine, imidazole, and pyri...

Gordon Bell, William Il. Strecker November 8, 1975 COMPUTER STRUCTURES: WHAT HAVE WE LEARNED FROM THE PDP-ll? Over the FDP-11’S six year life about 20,000 specimens have been built based on 10 species (models). Al though range was a design goal, it was unquantified; the actual range has exceeded expectations (5OO:l in memory size and system price]. The range has stressed the baa ic mini (mall c...

This booklet consists of the addresses delivered at the opening of the new laboratory for biochemical research at McLean Hospital. Cecil K. Drinker reviews the history of research at McLean Hospital. Jordi Foich surveys biochemical research in psychiatry with emphasis on his own contributions to the chemical constitution of the brain. The record of reasearch at the Psychiatric Service of the Ma...

The Strecker degradation reaction was evaluated as a means of modifying hemoglobin in vitro, utilizing ninhydrin as a model compound. Ninhydrin led to modification of hemoglobin (when incubated with hemoglobin or red cells) at physiologic temperature and pH. Isoelectric focusing documented the formation of new hemoglobin bands, all with decreased (more negative) isoelectric points that hemoglob...

Pregnancy and the post-partum period are generally regarded as maturational crises equal in importance to those of adolescence and the menopause. Stresses undergone during this period include (a) endocrine changes, (b) activation of unconscious psychological conflicts pertaining to pregnancy and (c) the intrapsychic reorganization ofbecorning a mother. In light of this, it seems likely that cli...