This thesis will focus on applying smoothing splines to magnetic resonance image (MRI) analysis. Some additional work on support vector machine with a hybrid loss function will be discussed. We apply smoothing splines to both the structural MRI and functional MRI. For the structural MRI, we fit thin plate splines to overlapping blocks of the image with different configurations of knots. The opt...

Periodic cellular configurations with negative Poisson’s ratio have attracted the attention of several researchers because of their superior dynamic characteristics. Among the geometries with a negative Poisson’s ratio, the chiral topology features localized deformed configurations when excited at one of its natural frequencies. This is of particular importance as resonance can be exploited to ...

In previous work, we introduced the concept of structural clone as recurring configurations of simple clones (i.e., similar code fragments). We also described a technique for detection of certain types of structural clones. The premise of our approach is that structural clones can provide a higher level and more useful view of the similarity situation in software than simple clones alone. In th...

This article argues for a historical-structural approach to explaining conflict and settlement. It argues that the manner in which institutions function and actors pursue their ends is in part determined by slow-moving inter-linked structural relationships whose logic, trajectory and effects can only be identified historically. In complex conflicts such structural configurations generate tenden...

Density functional theory (DFT) based calculations have been performed to examine the relaxations of tautomers of 4–hydroxy–6–methylpyridin–2(1H)–one (MPO), as a representative of pyridinone derivatives, at the fullerene (C60) surfaces. Optimized molecular properties including energies, dipole moments and atomic scale quadrupole coupling constants (CQ) have been e...

This paper presents numerical modeling technique for Dhajji-Dewari structures (timber-braced rubble stone masonry), and its application for the evaluation of in-plane force-deformation capacity of Dhajji wall panels of different configuration of bracings. Dhajji structures are mainly composed of vertical and horizontal timber posts and braced using diagonal bracings and horizontal studs. Wall o...

The present study assesses the seismic performance of steel moment resisting frames (SMFs) retrofitted with different bracing systems. Two structural configurations were utilized: ordinary concentrically braces (OCBFs), buckling-restrained braces (BRBFs). A 7-story and 18-story steel perimeter SMFs were designed with insufficient lateral stiffness to satisfy code drift limitations in high seism...

Disposition and transportation of anticancer drugs by human serum albumin (HSA) affects their bioavailability, distribution and elimination. In this study, the interaction of a set of anticancer drugs with HSA was investigated by molecular dynamics and molecular docking simulations. The drugs' activities were analyzed according to their docking scores, binding sites and structural descriptors. ...

Yuanxin Liu: Computations of Delaunay and higher order triangulations, with applications to splines. (Under the direction of Jack Snoeyink.) Digital data that consist of discrete points are frequently captured and processed by scientific and engineering applications. Due to the rapid advance of new data gathering technologies, data set sizes are increasing, and the data distributions are becomi...