*Corresponding author: Email: [email protected], [email protected]

*Corresponding author: Email: [email protected]

*Corresponding author: Email: [email protected]

That the effect of a treatment will vary among subjects is not surprising, nor is it a recent concept. Roses provided an 1892 quote by Sir William Osler, ‘‘If it were not for the great variability among individuals medicine might as well be a science and not an art.’’ Subject–treatment (S–T) interaction is, as the term implies, an interaction of specific subjects with applied treatment(s). The ...

Aaronson, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Abdu, Hassen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Abouraddy,Ayman F. . . . . . . . . . ....

Subjects model diierent perspectives on a problem domain by collections of related class hierarchies. Subjects can be seen as the result of separate and possibly independent development processes for partial models. The subjects can be eeciently composed by a technique that builds on the notion of roles. The composition allows already combined subjects to be further combined or to be dissolved ...

Abouraddy,Ayman F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Adalsteinsson, Elfar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Adam,A. J. L. . . . . . . . . . . . . . . ....