a number of theories about the hest method of allocating assets have been developed over the years, managers are concernd about allocating scarce resources, mainly capital, in most productive way. managers want to ensure that the return from the invested resources exceeds the cost of resources finanical theories and finanicial strategies try to facilitate creating optimum value for investors in...

background although liver transplantation is the last resort for treating end stage liver diseases, this medical procedure is not available for all needful patients because of inadequate organ supply. therefore, guidelines have been developed by medical experts to regulate the process. some professionals believe that medical criteria are inadequate for organ allocation in all situations and may...

Rituximab is an effective treatment of rheumatoid arthritis (RA), which has been approved for the treatment of moderate to severe disease in patients with an inadequate response to anti-TNF therapies. Rituximab differs from other available biological agents for RA by way of its unique mode of action and unrivalled long dosing interval. The efficacy of rituximab subsides progressively over time ...

Nowadays, the advantages of virtual enterprises and collaborative networks are well known by scientists and professional communities. Despite the advantages, only a few networks continue running businesses after stopping the governmental subsides. One of the reasons is the lack of a model that evaluates the benefit from the firm’s point of view. The objective of this work is to develop a model ...

Vertigo is defined as a rotational sensation associated with nystagmus and often accompanied by nausea and vomiting, and somatic instability such as gait disturbance1. In patients with vertigo that occurs suddenly and subsides rapidly (within 24 hour) the caloric test, a vestibular dysfunction test, is generally negative. Because its underlying disease is poorly understood, and does not satisfy...

et al. [1] have shown that, on preand post-treatment evaluation of the lymph nodes, infiltration of Ki67and CD3-positive, CD8-positive, granzyme B-positive T cells increases. It has been observed that, in patients with Hodgkin lymphoma who are treated with lenalidomide and who develop TFR, cytokines (particularly interleukin [IL]-6, IL7, APRIL, BAFF/BLyS) are released because of B cell activati...

Six patients with blowout fractures of the orbital floor, not associated with infraorbital rim fractures, are presented. Diplopia, infraorbital anesthesia and enophthalmos following blunt trauma to the eye should alert the examiner to the possibility of a blowout fracture with incarceration of extraocular tissues. Early roentgenographic examinations are often difficult to evaluate because of pe...

As demonstrated by various investigators (Carter and Maclagan, 1946; Stillerman, 1948; Poulsen, 1949; Kalbak, 1951), the thymol reaction is positive in rheumatoid arthritis patients at a somewhat advanced and active stage of the disease. This positive reaction is assumed to be due to changes in the serum proteins. Patients with rheumatoid arthritis generally show marked changes in the serum pro...

CD4 T cells potentiate the inflammatory or humoral immune response through the action of Th1 and Th2 cells, respectively. The molecular basis of the differentiation of these cells from naive T cell precursors is, however, unclear. We found that GATA-3 was selectively expressed in Th2 cells. GATA-3 is expressed at a high level in naive, freshly activated T cells and Th2 lineage cells, but subsid...