When RNA polymerase II (RNAP II) is forced to stall, elongation complexes (ECs) are observed to leave the active pathway and enter a paused state. Initially, ECs equilibrate between active and paused conformations, but with stalls of a long duration, ECs backtrack and become sensitive to transcript cleavage, which is stimulated by the EC rescue factor stimulatory factor II (TFIIS/SII). In this ...

PURPOSE This study aims to examine how inequalities in suicide by education changed during and after macroeconomic restructuring following the economic crisis of 1997 in South Korea. MATERIALS AND METHODS Using Korea's 1995, 2000, and 2005 census data aggregately linked to mortality data (1993-2006), relative and absolute differentials in suicide mortality by education were calculated by gend...

Objectives: The predictive value of some preoperative inflammatory markers for postoperative infective complications in urinary system stone disease has been demonstrated. We investigated how valuable the systemic immune-inflammation index (SII) is as a marker development response syndrome (SIRS) patients undergoing ureteroscopy. Methods: data 495 who met study criteria were evaluated retrospec...

According to earlier research, tumour response, Lymphocytopenia, and a system-wide immune-inflammatory indexes all affect the clinical results of Stage III NSCLC. We postulated that response CRT would be related hematologic parameters could perhaps anticipate results. Retrospective evaluation stage NSCLC patients treated at single facility between 2015 2020 was done. After receiving CRT, pre-tr...

Aim: to evaluate the dynamics of leukocyte inflammatory markers in patients with ST-elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) depending on ejection fraction left ventricular (LV). Material and methods. The study group consisted 23 consecutive STEMI admitted Regional Clinical Cardiology Center Chernivtsi, who underwent successful reperfusion treatment...

The volatility and uncertainty in the process of technological developments are growing faster than ever due to rapid technological innovations. Such phenomena result in integration among disparate technology fields. At this point, it is a critical research issue to understand the different roles and the propensity of each element technology for technological convergence. In particular, the net...

OBJECTIVES To describe emergency department (ED) visits for self-inflicted injury (SII) among adolescents, examine trends in SII mechanisms, and identify factors associated with increased risk. METHODS Analyses included patients aged 10 to 18 years from the National Trauma Data Bank, years 2009 to 2012. We used Cochran-Armitage trend tests to examine change over time and generalized linear mo...

Background and Aims The multikinase inhibitor sorafenib is the only currently approved drug for the indication of advanced hepatocellular carcinoma (HCC). It provides a limited gain in survival time but is frequently associated with adverse events. We currently lack simple prognostic factors in sorafenib-treated HCC patients. Various inflammation-based scores (IBSs) have been evaluated as predi...

Purpose The purpose of this paper is to highlight challenges for service firms communicating Environmental, Social and Governance (ESG) efforts customers. Specifically, it focuses on the relationship between ESG metrics reporting customer perceptions social innovativeness. Design/methodology/approach empirical material comprises three years data (2018–2020) covering more than 100 from sources: ...

BACKGROUND There is a growing international literature assessing inequalities in health and mortality by area based measures. However, there are few works comparing measures available to inform research design. The analysis here seeks to begin to address this issue by assessing whether there are important differences in the relationship between deprivation and inequalities in mortality when mea...