This Part II paper describes the disintegration and dissolution aspects of the qualification of a new hypromellose capsule (HPMC Shell 2). This new capsule does not contain any gelling agent, and is manufactured by a thermal gelation process. Rupture time of the carrageenan-containing capsule (HPMC Shell 1) and HPMC Shell 2, as measured by an improved real-time detection method, showed only sli...

The goal of this study was to assess the relationship between Aβ deposition and white matter pathology (i.e., white matter hyperintensities, WMH) on microstructural integrity of the white matter. Fifty-seven participants (mean age: 78±7 years) from an ongoing multi-site research program who spanned the spectrum of normal to mild cognitive impairment (Clinical dementia rating 0-0.5) and low to h...

CONTEXT In some cases, synchronous superior mesenteric-portal vein resection can be performed during pancreatic resection for cancer. The reconstruction technique is usually primary anastomosis; in only a few cases is an autologous vein graft needed. CASE REPORT We report a case of reconstruction of the superior mesenteric-portal vein with a splenic vein autograft in a patient affected by pan...

BACKGROUND Prospective trials support the role of capsule enteroscopy as an improvement in diagnosing mucosal lesions in the small bowel. AIM To determine the diagnostic yield and safety of capsule enteroscopy vs. alternative diagnostic modalities (such as push enteroscopy, small bowel follow-through or enteroclysis) in patients with small bowel diseases. METHODS A search for prospective st...

SUMMARY Little is known about the long-term fate of acellular dermal matrices in breast implant surgery. A 12-year follow-up case with tissue analysis of AlloDerm in revision breast reconstruction reveals retention of graft volume and integration with an organized collagen structure, minimal capsule formation, and little or no indication of inflammation.

Dehiscence of the cochlear otic capsule has recently been described as a pathologic entity. We describe two cases of cochlear-facial dehiscence, which are the first reported: a 69-year-old male who complained of hearing loss, autophony, and pulsatile tinnitus and a 41-year-old female who complained of left-sided hearing loss, pulsatile tinnitus, and vertigo. In both, computed tomography (CT) sh...

In inverse problems, an extensive number of ground truth samples for the training supervised deep learning models is seldom available. Unsupervised approaches, like Deep Image Prior, offer a valuable alternative in this case. our work, we combine idea Prior with recently proposed capsule networks. The new model tested against standard convolutional on different image processing tasks and comput...

Abstract Late spontaneous hematoma (> 6 months postoperatively) after breast reconstruction using implant is rare complication. We experienced a case of capsular contracture with unique clinical form intracapsular 13 years implantation smooth saline filled implants. This report presented the mechanism complication examined through chart-review, histological morphological analysis, and litera...