The primary objective of this study was to quantitatively investigate the human perception of surface curvature by using virtual surfaces and motor tasks along with data analysis methods to estimate surface curvature from drawing movements. Three psychophysical experiments were conducted. In Experiment 1, we looked at subjects' sensitivity to the curvature of a curve lying on a surface and chan...

A new algorithm for approximation of a given surface or scattered points by a surface of revolution is presented. It forms the basis for a study of approximation with profile surfaces. Those are sweeping surfaces traced out by a planar curve when its plane is rolling on a developable surface. Important special cases include developable surfaces and pipe surfaces, where the moving curve is a str...

The authors report on the variability in the integrated quantity of free (unbound) plasma cisplatin (area under curve of plasma concentration versus time, AUC). The AUC was measured in 19 patients receiving cisplatin doses proportional to body surface areas (BSA), 30 mg/m2 over 1 hour. The relative standard deviation (RSD, population standard deviation divided by mean value) for the maximum fre...

  Application of gepraphic information system and image processing in evaluation of surface runoff of a watershed in recent years has increased greatly. In the study , the runoff curve number map was prepared using geographic information system (GIS)and Landsat Sattelite Images (ETM+)for two watersheds of Mansourabad in southern Khorasan province and Navroud in Gilan province based on the facto...

In order to study the dynamic meshing characteristics of the elliptic cylinder gear and obtain the meshing error of the gear transmission system, the two-dimensional static contact analysis of the gear tooth surface is carried out by using ANSYS software, and the key parts of the contact area of the tooth surface are determined. Then, the dynamic meshing model of the elliptic cylinder gear is e...

PURPOSE To evaluate the best method for dosing busulfan in children, we retrospectively analyzed two different data sets from three different dosing regimens by means of population pharmacokinetics using NONMEM. EXPERIMENTAL DESIGN The development data set consisted of plasma samples from 94 children, in the age range of 0.4 to 18.8 years, receiving either oral or intravenous busulfan. The ex...

This paper shows how to construct a rational Bezier model of a swept surface that interpolates N frames (i.e., N position/orientation pairs) of a fixed rational space curve c(s) and maintains the shape of the curve at all intermediate points of the sweep. Thus, the surface models an exact sweep of the curve, consistent with the given data. The primary novelty of the method is that this exact mo...

This paper presents a novel approach that automatically generates interference-free tool path for five-axis flank milling of ruled surface. A boundary curve of the machined surface is subdivided into curve segments. Each segment works as a guide curve in the design method for developable Bézier surface that controls a developable patch for approximating the surface with available degrees of fre...

Interactive tools for segmenting D and D images are presented These tools allow a user to quickly revise a segmentation result obtained from an automatic method A thresholding technique is described that nds a unique threshold value for each homogeneous region in an image The threshold value is found such that variance in the region is minimized under change in the threshold value Curve and sur...

In a recent review, Mathijssen et al. [1] proposed using flatfixed dosing regimens rather than body surface area (BSA)based dosing for anticancer drugs because “it does not seem worse than using BSA-based dosing” with regard to pharmacokinetic variability. We feel that this statement, together with other recent publications arguing against BSAbased dosing, requires a counterpart. Most cytotoxic...