Molecularly imprinted polymers (MIPs) have been playing an increasingly important role in volatile organic compounds (VOC) sensing for air quality control. The unique feature of these materials is their biomimetic molecular recognition functionality. Theoretical chemistry can advance our ability to design and synthesize new MIPs with specific functions, providing valuable insight into the syste...

Highly sensitive flow-injection chemiluminescence (CL) combined with molecularly imprinted solid-phase extraction (MISPE) has been used for determination of 2,4-dichlorophenol (2,4-DCP) in water samples. The molecularly imprinted polymer (MIP) for 2,4-DCP was prepared by non-covalent molecular imprinting methods, using 4-vinylpyridine (4-VP) and ethylene glycol dimethacrylate (EGDMA) as the mon...

Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly imprinted solid-phase extraction (MISPE) followed by liquid chromatography-mass spectrometry (LC-MS) for biomarker determination using ProGastrin Releasing Peptide (ProGR...

A novel molecularly imprinted optosensing material based on multi-walled carbon nanotube-quantum dots (MWCNT-QDs) has been designed and synthesized for its high selectivity, sensitivity and specificity in the recognition of a target protein bovine serum albumin (BSA). Molecularly imprinted polymer coated MWCNT-QDs using BSA as the template (BMIP-coated MWCNT-QDs) exhibits a fast mass-transfer s...

Hydrogel-based molecularly imprinted polymers (HydroMIPs) were prepared for several proteins (haemoglobin, myoglobin and catalase) using a family of acrylamide-based monomers. Protein affinity towards the HydroMIPs was investigated under equilibrium conditions and over a range of concentrations using specific binding with Hill slope saturation profiles. We report HydroMIP binding affinities, in...

Here we report an electrochemical sensor for the determination of picric acid (PA) based on molecularly imprinted polymer (MIP) reduced graphene oxide (rGO) coated pencil graphite electrode (PGE). Pyrrole (Py) was electropolymerized surface rGO modified PGE, where PA used as template. After extraction molecules from matrix, MIP|rGO|PGE obtained. Computational studies were carried out to predict...

The aim of the work is to design and synthesize and evaluate the polymer recognition characteristics of molecularly imprinted polymers selective for trans-retinol (R-MIP). The optimal amount of template and methacrylic acid (MAA) functional monomer as well as ethylene glycol dimethacrylate (EDMA) acts as the crosslinker was examined toward imprinting process using radical polymerization in chlo...