Novel lipid nanoparticulates (NCs) were developed by a combined approach of precipitation and complexation with an aim to improve the solubility, stability and targeting efficiency of glimepiride (GLP). GLP NCs were prepared by precipitation process using PEG 20000 and further complexed with phospholipon90G (P90G). The NCs were evaluated for physicochemical characterization, such as drug lo...

in this article, finite difference method (fdm) is used to solve sixth-order derivatives of differential equations in buckling analysis of nanoplates due to coupled surface energy and non-local elasticity theories. the uniform temperature change is used to study thermal effect. the small scale and surface energy effects are added into the governing equations using eringen’s non-local elasticity...

Density functional theory (DFT) based calculations have been performed to examine the relaxations of tautomers of 4–hydroxy–6–methylpyridin–2(1H)–one (MPO), as a representative of pyridinone derivatives, at the fullerene (C60) surfaces. Optimized molecular properties including energies, dipole moments and atomic scale quadrupole coupling constants (CQ) have been e...

AIM To investigate the mechanical and chemical alterations of Invisalign appliances after intraoral aging. MATERIALS AND METHODS Samples of Invisalign appliances (Align Technology, San Jose, California, USA) were collected following routine treatment for a mean period of 44±15 days (group INV), whereas unused aligners of the same brand were used as reference (group REF). A small sample from t...

Potential applications of metal nanoparticles, because of specific physical or chemical properties, are in close relationship to their structural peculiarities. Structural characterisation of nanoparticles in various configurations, using high resolution electron microscopy (HREM), may reveal detailed information on particle shape and planar lattice defects. The variations observed for most nob...

This paper focuses on the recent advances on radiolysis-assisted shape-controlled synthesis of noble metal nanostructures. The techniques and protocols for producing desirable shapes of noble metal nanoparticles are discussed through introducing the critical parameters which can influence the nucleation and growth mechanisms. Nucleation rate plays a vital role on the crystallinity of seeds whil...

introduction: gully erosion is an important type of soil erosion in iran and ardebil province (moghimi and salami, 2011; khatibi, 2006). increasing the cross section of gullies is an indicator for gully developing (deng et al, 2015). topography and soil properties are two important factors in gully developing in various regions of worldwide (poesena et al, 2003). despite the importance of soil ...

Biochar, a co-product of a controlled pyrolysis process, can be used as a tool for sequestering C in soil to offset greenhouse gas (GHG) emissions, and as a soil amendment. Whereas the impacts of biochar application on soil chemical properties are widely known, the research information on soil physical properties is scarce. The objectives of this review are to (i) synthesize available data on s...

Mitochondrial membrane potential varies, depending on energy demand, subcellular location, and morphology and is commonly used as an indicator of mitochondrial functional status. Electrophoretic mobility is a heterogeneous surface property reflective of mitochondrial surface composition and morphology, which could be used as a basis for separation of mitochondrial subpopulations. Since these pr...