INTRODUCTION Among surgical oncology patients, incisional surgical site infection is associated with substantially increased morbidity, mortality and healthcare costs. Moreover, while adults undergoing pancreaticoduodenectomy with preoperative placement of an intrabiliary stent have a high risk of this type of infection, and wound protectors may significantly reduce its risk, no relevant studie...

Background: Surgical site infections are important cause of morbidity and mortality in admitted patients world over. Objectives: To determine the pattern of surgical site infections in General Surgical ward of a tertiary care hospital. Study type, settings and duration: Analytical cross-sectional study conducted at Department of General Surgery, Pakistan Institute of Medical Sciences, Islamabad...

introduction : surgical removal of third molar is one of the most common surgical procedures in oral surgery and is often associated with complications such as pain, swelling and trismus. the main purpose of the study was to assess  the  therapeutic  effect  of  low  level  laser  (lll)  irradiation  on postoperative edema and wound healing compared to routine postoperative management after thi...

Background: Wound infection has become a major medical problem in recent years. This is usually caused by Gram-positive bacteria, especially Staphylococcus aureus. Since antimicrobial resistance to current drugs has critically been developed in these causative microorganisms, substitution medicine has become one of the main interests within  researchers. OBJECTIVES: The aim of this study was to...

BACKGROUND Matrix metalloproteinases (MMPs) are crucial in the inflammatory and remodeling phases of wound healing. We previously reported the correlation between pro-inflammatory cytokines and timing of successful combat-wound closure. We now extend our studies to investigate the correlation between wound-remodeling MMP expression and wound healing. METHODS Thirty-eight wounds in 25 patients...

Painful acute cysts in the natal cleft or lower back, known as pilonidal sinus disease, are a severe burden to many younger patients. Although surgical intervention is the preferred first line treatment, postsurgical wound healing disturbances are frequently reported due to infection or other complications. Different treatment options of pilonidal cysts have been discussed in the literature, ho...

CONTEXT Despite the routine use of prophylactic systemic antibiotics, sternal wound infection still occurs in 5% or more of cardiac surgical patients and is associated with significant excess morbidity, mortality, and cost. The gentamicin-collagen sponge, a surgically implantable topical antibiotic, is currently approved in 54 countries. A large, 2-center, randomized trial in Sweden reported in...