نتایج جستجو برای: sustained release tablets

تعداد نتایج: 299466  

2010
J. Ayyappan Darlin Quine

Directly compressible co-processed sustained release multifunction agent [DCCSRA] comprising povidone and glyceryl behenate in the ratio of 1:1, 1:2 and 1: 3 were prepared and evaluated. The DCCSRA exhibited good flow and compressibility. The DCCSRA served as a retardant, binder and lubricant in Gliclazide sustained release tablets. By optimization of DCCSRA quantity in formulation, the drug re...

2010
Rajat Kar Snehamayee Mohapatra Satyabrata Bhanja Debjyoti Das Bhaktibhusan Barik

In the present investigation an attempt has been made to increase therapeutic efficacy, to reduce frequency of administration and to improve patient compliance by developing a sustained release matrix tablets of isosorbide-5-mononitrate. Sustained release matrix tablets of isosorbide-5-mononitrate were developed by using different drug: polymer ratios, such in F1 (1:0.75), F2 (1:1), F3 (1:1.5),...

Journal: :Journal of applied pharmaceutical research 2022

Tablet is most popular among all dosage forms today because of its convenience, ease administration, greater flexibility in form design, production, and low cost non-invasive therapy. Formulation tablets requires API along with excipients. Excipients include lubricants, diluents, binders, glidants, disintegrants, sweetening agents, flavoring etc. Recent trends indicate that multi-particulate dr...

2012
K. Kannan

Lowering elevated blood pressure (BP) with drug therapy reduces the risk for catastrophic fatal and nonfatal cardiovascular events. Due to the marked variability in an individual patient’s BP response and low response rates with monotherapy, expert groups such as Joint National Committee (JNC) emphasize the value of combination antihypertensive regimen, usually of different classes, having addi...

Journal: :iranian journal of veterinary medicine 0
sakineh khanamani falahatipour department of pharmacology, faculty of veterinary medicine, university of tehran, tehran, iran ali rasooli department of pharmacology, faculty of veterinary medicine, university of tehran, tehran, iran yalda hosseinzadeh ardakani .department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran hamid akbari javar associate prof. dept pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran. katayoun kiani dept pharmacology, faculty of vet med, university of tehran, tehran, iran. taghi zahraee salehi prof. and head of dept microbiology, faculty of vet med, university oftehran, tehran, iran.

background: the development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-gp) solutions due to their good biodegradability and thermosensitivity. objectives: the general aim of this study was to prepare a novel in si...

Journal: :research in pharmaceutical sciences 0
j. emami j. varshosaz f. ahmadi

in recent years, great efforts have been devoted to the design of drug delivery systems. many polymeric excipients have been studied in order to make drug release fit the desired profiles. the aim of this work was to design a theophylline oral suspension, as sustained release pharmaceutical preparation in order to decrease the plasma level fluctuations and adverse effects of theophylline. micro...

Journal: :iranian journal of pharmaceutical sciences 0
fatemah atyabi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran afsaneh mohammadi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran rassoul dinarvand department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran

the purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (ec) as a carrier polymer through an emulsion solvent evaporation method. these evaluations characterized the pattern of drug release from prepared microspheres. nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. the effect of process variab...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2006
Mamoru Fukuda Nicholas A Peppas James W McGinity

The purpose of this study was to investigate the influence of sodium bicarbonate on the physicochemical properties of controlled release hot-melt extruded (HME) tablets containing Eudragit RS PO and/or Eudragit E PO. Acetohydroxamic acid and chlorpheniramine maleate were used as model drugs. Sodium bicarbonate was incorporated into the tablet formulations and the drug release properties and buo...

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