Abstract Introduction Pediatric burns commonly involve the face and periocular areas, with a risk of impairing vision. The aim this study is to characterize ocular injuries in burn patients identify at most complications. Methods This retrospective review within single academic, urban pediatric center. All under 18 years age admitted from January 2010 December 2020 periorbital or involvement we...

PURPOSE This retrospective observational case series of fifty-one consecutive patients referred to the eye clinic with acute-stage Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) from 1995 to 2011 examines the effect of early treatment with a systemic corticosteroid or intravenous immunoglobulin (IVIG) on the ocular outcomes in patients with SJS or TEN. METHODS All patients...

Our patient was diagnosed with cicatricial pemphigoid (CP) in 2001. She demonstrated classic clinical findings and underwent biopsies that supported this diagnosis. She unfortunately experienced severe CP involving both of her eyes, oral mucosa, pharyngeal mucosa, and esophagus. Her left eye was seriously affected early in the course of her disease. She experienced significant scarring of the c...

Background: Ocular chemical burns induce devastating and permanent damage to the ocular surface. Rapid intervention is required for maximal visual rehabilitation. Amniotic membrane transplantation (AMT) may save the ocular surface, however it introduces a potentially unnecessary surgical trauma in such compromised eyes. Amniotic membrane extracts (AME) could be a practical substitute of AMT in ...

The study of chemical behavior includes answering questions as ’which isomer is the most stable?’, ’which relative orientation is the most favorable for such-and-such interaction?’, ’which conformer is the global minimum?’, ’what are the lowest energy configurations and their relative energies?’. The answer to these questions–and many others–depends on the ability to find and study a variety of...

The need for development of new approaches for defect/fault analysis of VLSI circuit is growing and becomes even more important as we move further into the sub-micron devices. Yield loss in ICs fabrication and testing of the manufactured ICs now are major bottlenecks in the production of qualitative VLSI circuits. For instance, it is predicted that the test costs for the emerging deep submicron...

Mucous membrane pemphigoid (MMP, formerly cicatricial pemphigoid) is a chronic autoimmune, sub-epithelial blistering disease usually of middle aged or elderly patients, more common in women. The prevalence is uncertain and the aetiology is still unknown. Target antigens are epithelial basement membrane proteins BPAG-1, BPAG-2, laminin-331, and laminin-332 [1]. Oral and conjunctival membranes ar...

Purpose To evaluate the prognosis in Chinese patients with conjunctival melanoma and determine its predictors. Further, to explore the racial differences in clinical characteristics and outcomes between Chinese and Caucasian patients. Methods This cohort study included 57 eyes of 57 consecutive patients with pathologically verified conjunctival melanoma between 1996 and 2016. Medical records ...

A 41-year-old man presented with a 24 hour history of a painful right eye. Nineteen months previously he had splashed molten lead into this eye. He had subsequently undergone mucous membrane grafting to repair scarred conjunctival fornices. A vascularised cornea remained with associated cicatricial entropion preventing eyelid closure. He underwent further upper fornix reconstruction using mucou...

I read with great interest the recent article by Sinha et al.1 Interestingly, one rare condition that often mimics dyskeratosis congenita, and that needs to be distinguished from it, is Kindler Syndrome (KS). KS primarily occurs secondary to "loss of function" mutations in the FERMT1 gene. Mode of inheritance is autosomal recessive. Interestingly, FERMT1 gene mutations are absent in 30% of case...