Background: Primary cutaneous T cell lymphoma is a diverse and rare group of diseases with clinical manifestations that, if not biopsied, are easily confused benign skin diseases. Objective: To determine some features primary lymphomas classify them according to the 2018 update World Health Organization European Organisation for Research Treatment Cancer classification. Methods: case series stu...

Although lymphoma is predominantly a disease affecting the traditional sites of lymph nodes, liver, spleen and bone marrow, it can affect many other sites, which is one of the fascinations of the disease. There are many case reports in the literature of lymphoma affecting unusual sites, and this is particularly true of T/NK cell lymphomas and those associated with HIV infection. Even within the...

Abstract T-cell lymphomas are rare neoplasms that have complex pathology. The multiparameter approach has been recommended by World Health Organization (WHO) for the classification of taking into account morphology, immunophenotype, genetics, and clinical features. This also includes division established on possible cell-of-origin (COO) from T regulatory or T-follicular helper (TFH) cells. rece...

Except for ALK-positive anaplastic large cell lymphoma (ALCL) and patients with limited disease, mature T- and natural killer (NK) cell lymphomas are disorders with a poor prognosis. Patients with relapsed or refractory ALK-negative ALCL, angioimmunoblastic T-cell lymphoma (AITL), or peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) after allogeneic transplantation of hematopoietic...

Advanced T-cell non-Hodgkin's lymphoma in adults has been found to have a poor outlook with conventional chemotherapy. To see if this extends to patients treated with high dose therapy and autologous hematopoietic stem cell transplantation, we reviewed the results with this treatment approach at our institution. From October, 1983, to May, 1988, 41 patients who underwent high-dose therapy and a...

Primary gastrointestinal T-cell lymphoma is an uncommon entity and primary colon T-cell lymphoma is even rarer. The majority of enteropathy-associated T-cell lymphomas present predominantly as ulcers or strictures in the endoscopic examinations, while primary B-cell lymphomas commonly present as exophytic lesions. Ulcerative colon T-cell lymphoma may mimic Crohn's disease (CD), which is a chron...

Primary small intestinal malignancies are rare and accounting for 1-2% of all gastrointestinal (GIT) tumors. Extranodal lymphomas most commonly found in GIT with majority sites stomach, intestine ileo-cecal junction. Non-Hodgkin’s Lymphoma (NHL) predominantly B cell type constituting 90% cases few T type. The purpose this editorial is to highlight the morphology rarity lymphoma encountered jeju...

The advances in low-grade lymphoma & T-cell lymphoma from the 2008 ASH meeting were presented. These included therapeutic regimens for low grade lymphoma, frontline bendamustine plus rituximab data, radioimmunotherapy consolidation in advanced disease, idiotype vaccine, and other novel therapeutic agents such as next generation anti-CD20 GA101, syk inhibitor Fostamatinib in treatment of low-gra...