Lathyrogens decrease collagen and elastin cross-linking by inhibiting lysine oxidase. The lathyrogens isoniazid and semicarbazide decrease liver pyridoxal phosphate and are teratogenic; all their effects are reversed by pyridoxal. beta-Aminopropionitrile, another lathyrogen, does not affect liver pyridoxal phosphate, and its lathyrogenic and teratogenic effects are not reversed by pyridoxal. Ti...

UNLABELLED Counselling or prescribing drugs during pregnancy requires health professionals to assess risk/benefit ratio for women and their baby. A misperception of the risk may lead to inappropriate decisions for pregnancy outcomes. The aim of the present study was to assess teratogenic and/or foetotoxic risk perception of common medications by general practitioners (GPs) and community pharmac...

The COVID-19 pandemic started in China at the end of year 2019 and spread across all continents. Little is known about effect COVID19 infection on pregnancy its fetal outcome. In this case report A Multigravida was diagnosed As positive first trimester, followed through her delivered a full-term normal baby without any complications. This encourages us to continue COVID 19 woman who come contac...

Valproic acid, or dipropylacetic acid, and its salt, sodium valproate, are used to treat a wide variety of seizure disorders. Until recently there was no convincing evidence demonstrating a teratogenic effect in humans. However, the association between other anticonvulsant drugs and congenital malformations has been recognized for more than a decade,I,2 and this, together witfI tbe lack of conv...

Drugs administered to the mother can affect the fetus by preventing implantation or by causing resorption of the embryo, abortion or intrauterine death. It is a sobering thought that the first of these mechanisms is dignified by the name 'contraception' and that the remainder have far less medicolegal and economic significance than the survival of a defective fetus after a less drastic chemical...

Received: October 06, 2017 Revised: January 03, 2018 Accepted: February 02, 2018 Abstract: Introduction: Due to release of pollutants, chemical or hazardous materials into the environment from manmade or artificial sources, human being as well as animal populations are affected directly or indirectly through inhalation of air, intake of water, intake of food, dermal contact, etc. Then, human be...

Dermatologist Michael McIntyre enters the examining room and greets his patient, Reina Sharpe, and her parents. Reina is 14 years old and has been a patient of Dr. McIntyre’s for about a year. Anxious about beginning her freshman year of high school in a few weeks, Reina expresses frustration over her worsening acne. Dr. McIntyre recognizes that Reina’s condition has progressed from a moderate ...