OBJECTIVE To examine incident-reporting items in tertiary hospitals using the framework of the World Health Organization's International Classification for Patient Safety (ICPS). DESIGN Cross-sectional survey. SETTING AND PARTICIPANTS Forty acute-care tertiary hospitals in Korea (response rate = 90.9%). METHODS Data were collected using a semistructured questionnaire during on-site interv...

Unprotected tertiary sulfonimidamides have been prepared in good to excellent yields in a one-pot transformation from tertiary sulfinamides through NH transfer. The reaction is mediated by commercially available (diacetoxyiodo)benzene and ammonium carbamate in methanol under convenient conditions. A wide range of functional groups are tolerated and initial results indicate that the NH transfer ...

PURPOSE The increasing prevalence and global spread of carbapenem-resistant Acinetobacter baumannii (A. baumannii) has become a serious problem. The aim of this study was to investigate molecular and epidemiological characteristics of carbapenem-resistant A. baumannii isolates collected from Korean non-tertiary hospitals. MATERIALS AND METHODS Thirty six non-duplicated carbapenem-resistant A....

The first regio-, diastereo-, and enantioselective allylic alkylation of acyclic β-ketoesters to form vicinal tertiary and all-carbon quaternary stereocenters is reported. Critical to the successful development of this method was the employment of iridium catalysis in concert with N-aryl-phosphoramidite ligands. Broad functional group tolerance is observed at the keto-, ester-, and α-positions ...

OBJECTIVES To study the caesarean section rate and the trends in indications for caesarean delivery at the Singapore General Hospital (SGH) during two study periods of 6 months each. MATERIALS AND METHODS The percentages of caesarean sections attributable to specific indications were computed for the first 6 months of 1998 and the last 6 months of 2001. Subgroup analysis of "less common indic...

Despite available guidelines on indications for fresh-frozen plasma (FFP) transfusion, inappropriate use is increasing worldwide. We evaluated FFP administration to patients admitted to the Steve Biko Academic Hospital over 4 months, including indications for use and completeness of requisition forms. Transfusions were considered inappropriate for 39.5% of units administered. Of request forms s...

OBJECTIVE Satisfaction of health service user is the most important aim for health provider. We observed and heard many dissatisfactory comments among people utilizing health services in Aseer Central Hospital, Saudi Arabia which led us to conduct this study to verify these comments. METHODS During a 12-month period (April 2001 - March 2002) we undertook a systematic sample collection on ever...

OBJECTIVE To determine the factors influencing cervical cancer diagnosis and treatment in countries of East, Central and Southern Africa (ECSA). METHODS Data were collected from randomly selected primary health care centres, district and provincial hospitals, and tertiary hospitals in each participating country. Health care workers were interviewed, using a questionnaire; the facilities for s...

Despite the extensive coordination chemistry of imidazoles, metal-mediated imidazole activation is very rare. It has been shown that deprotonation of the central C-H group of coordinated N-alkylimidazoles can serve, after reaction of the resulting imidazolyl intermediate with an electrophile, as a new synthetic route to N-heterocyclic carbene (NHC) complexes. NHC ligands, which attract much ong...

OBJECTIVE The improved availability of MRI in medicine has led to an increase in incidental findings. Unexpected brain MRI findings suggestive of multiple sclerosis (MS) without typical symptoms of MS were recently defined as radiologically isolated syndrome (RIS). The prevalence of RIS is uncertain. The aim of this study was to determine the prevalence of RIS at a university hospital in a regi...