In many seasonally breeding birds, female and male testosterone (T) levels peak at the start of the breeding season, coinciding with pair bonding and nesting activities. Shortly after the onset of egg laying, T levels slowly decline to baseline levels in both sexes, but more rapidly so in females. During this period, T in males may still function to facilitate territorial behaviour, mate guardi...

A number of studies have achieved the consensus that microwave thermal technology can regenerate the granular activated carbon (GAC) more efficiently and energy-conservatively than other technologies. In particular, in the microwave heating industry, permittivity is a crucial parameter. This paper developed two equivalent models to establish the relationship between effective complex permittivi...

1 IMARDepartment of Oceanography and Fisheries University of the Azores, Cais de Sta. Cruz, PT9901-862 Horta (Azores), Portugal 2 Laboratoire de Biologie et Environnement Marins, FRE 2727 du CNRS, Université de La Rochelle, 22, Avenue Michel Crépeau, F-17042 La Rochelle, France 3 Département Géosciences Marines, Centre de Brest de l’IFREMER, BP 70, 29280 Plouzane Cedex France 4 Departement Envi...

A new series of compounds containing a sulfamide moiety as zinc-binding group (ZBG) has been synthesized and tested for determining inhibitory properties against four human carbonic anhydrase (hCA) isoforms, namely, CAs I, II, IX, and XII. The X-ray structure of the cytosolic dominant isoform hCA II in complex with the best inhibitor of the series has also been determined providing further insi...

We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and undetectable IGF-1 levels had suggested GH deficiency, while response to therapy indicated GH insensitivity. Molecular evaluation of the GH/IGF-1 axis should be performed in these cases to improve diagnosis and therapy.

The IGF1 generation test (IGFGT) is often used during the assessment of suspected GH insensitivity (GHI). We report the results of a survey undertaken in 2010 to determine the use of IGFGT amongst members of the European Society for Paediatric Endocrinology to evaluate suspected GHI. The literature surrounding the usefulness and limitations of IGFGT are reviewed, and recommendations provided fo...

Introduction: Spinel minerals with 'normal' structure are common in extraterrestrial materials and can form via a large range of processes including nebular condensation, crystallization from liquid melts and sub-solidus metamor-phic reactions. Owing to their ability to accept a large range of cations in their crystal structures these minerals can be regarded as useful petrogenetic indicators w...

In his famous letter in 1870, Maxwell describes how Joule's law can be violated "only by the intelligent action of a mere guiding agent", later coined as Maxwell's demon by Lord Kelvin. In this letter we study thermodynamics of information using an experimentally feasible Maxwell's demon setup based a single electron transistor capacitively coupled to a single electron box, where both the syste...

•A seminoma developed in a patient with androgen insensitivity syndrome.•The patient had a de novo androgen receptor mutation.•Proper management of AIS, including appropriate genetic counseling, is necessary.

Abstract: We prove the existence and uniqueness of weak solutions to the variational formulation of the Maxwell-Boussinesq approximation problem. Some further regularity in W , δ > 0, is obtained for the weak solutions. The shape sensitivity analysis by the boundary variations technique is performed for the weak solutions. As a result, the existence of the strong material derivatives for the we...