We describe herein the first access to 12-membered cyclic[7,0]ortho,meta-diarylheptanoids. The key features of synthesis include both a Suzuki-Miyaura coupling and ring closing metathesis. Actinidione, promising natural product, along with bioactive tetracyclic derivative were obtained in 14 steps for time from cheap commercially available substrates an overall yield 18-21%. Our modus operandi ...

Herein, a copper(II)-catalyzed dearomative cyclization amination of N-(2-aminobenzoyl) indoles is presented. Under mild reaction conditions, the proceeds to afford tetracyclic indolines by forming new C−N bond in good yields. The 5a,6-dihydroindolo[2,1-b]quinazolin-12(5H)-ones are obtained excellent yields (up 99% yield) using trifluoromethanesulfonic acid (TfOH) mediated N−Ts cleavage. compoun...

the eccentricity connectivity index of a molecular graph g is defined as (g) = av(g)deg(a)ε(a), where ε(a) is defined as the length of a maximal path connecting a to othervertices of g and deg(a) is degree of vertex a. here, we compute this topological index forsome infinite classes of dendrimer graphs.

reaction of tryptamine 1 with dimethyl -3-methoxyallylidenemalonate 2 afforded n?-[4,4-bis (methoxycarbonyl)-1,3-butadienyl] tryptamine 3 which in combination with acetylchloride and pyridine in dichloromethane gave n?, n?-[acetyl]-[(4,4-dinethoxycarbonyl) 1,3butadienyl] tryptamine 4. treatment of 3 with sodium hydroxide afforded 2h[n-(3-indolyl) ethyl] 2-oxo-3-methoxycarbonyl-1-pyridine 5. cyc...

solvable graphs (also known as reachable graphs) are types of graphs that any arrangement of a specified number of agents located on the graph’s vertices can be reached from any initial arrangement through agents’ moves along the graph’s edges, while avoiding deadlocks (interceptions). in this paper, the properties of solvable graphs are investigated, and a new concept in multi agent moti...

A 14-membered macrocycle with an allene and a furan strategically located at across the ring from each other is synthesized using an allene ring closing metathesis reaction. Upon treatment of the macrocycle with a catalytic amount of Pd(OAc)(2) and other additives, the first transannular [4+3] cycloaddition occurred to yield 37% of a tetracyclic compound containing the ABC ring structure of the...