A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy. The serum bromide concentration was increased more than two-fold above the upper reference value. Clinical signs disappeared after applyin...

Three azolo[b]1,3,4-thiadiazinium bromides were prepared from the respective N-amino-N'-methylazolethiones and phenacyl bromide, and their crystal structures were determined. 6-Phenyl-1-methylimidazo[2,1-b]1,3,4-thiadiazinium bromide (1) crystallized as methanol solvate (P21/n), 6-phenyl-1-methyl-1,2,4-triazolo[3,4-b]1,3,4-thiadiazinium bromide (2) as hemi-ethanol solvate (P21/n), and 6-phenyl-...

High-performance IM-5 was prepared by tetrapropylammonium hydroxide (TPAOH) and NaOH alkaline treatment. The modification of combined treatment on the pore acidity were systematically characterized. 29Si NMR results indicated that Si(4Si, 0Al) sites protected cation (TPA+) at low TPAOH/(NaOH + TPAOH) molar ratio, while protection effect extended to some Si(3Si, 1Al) ratio 75%. And, amount stron...

A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy.The serum bromide concentration was increased more than two-fold above the upper reference value.Clinical signs disappeared after applying ...

The recent role of bromide as a residue in food and water necessitated its toxicological investigation. Although much was known already about the absorption, distribution and elimination of bromide, more data were required, especially for the rat. The pharmacokinetics in the rat were therefore investigated, with emphasis on cumulation and on the role of chloride in bromide elimination. This rev...