Thalassaemia is one of the most common genetic diseases worldwide, with at least 60,000 severely affected individuals born every year. Individuals originating from tropical and subtropical regions are most at risk. Disorders of haemoglobin synthesis (thalassaemia) and structure (eg, sickle-cell disease) were among the first molecular diseases to be identified, and have been investigated and cha...

The transition to parenthood is a substantial challenge for many couples, and the extent to which the partners can support each other and their relationship is strongly related to the sensitivity and responsiveness of their parenting of their infant. This paper critically analyses the links between the couple relationship and parenting of infants and reviews the research evaluating couple psych...

This article introduces the special section "New Research Findings on Emotionally Focused Therapy." Emotionally focused couple therapy researchers have a strong tradition of outcome and process research and this special section presents new findings from three recent studies. The first study furthers the goal of determining the kinds of clients for which EFT is effective (Denton, Wittenborn, & ...

Time-series analysis (TSA) is frequently used in order to clarify complex structures of mutually interacting panel data. The method helps in understanding how the course of a dependent variable is predicted by independent time-series with no time lag, as well as by previous observations of that dependent variable (autocorrelation) and of independent variables (cross-correlation).The study analy...

Thalassaemia is one of the most common inherited genetic disorders prevalent worldwide. In India, certain communities were identified with high risk of beta thalassaemia. There are more than 200 different types of beta thalassaemia mutations worldwide. The most common beta thalassaemia mutation, IVS 1-5 (G→C) is being analyzed here to get information whether this common mutation is prevailing a...

Background and Aims: Hepatitis C virus is one of the viral infections which is mainly transmitted by blood transfusion. Patients with thalassaemia frequently need blood transfusion and are in danger of HCV infection. In most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. Liver is the main site of HC...

In this study various abnormal haemoglobin fractions on HPLC were observed in 158 cases out of the total 300 screened paediatric anaemic cases. Of the 300 paediatric cases, samples analyzed on CE-HPLC for haemoglobinopathies, maximum 67 (22.33%) cases were diagnosed as S-β double heterozygous, 39(13%) as sickle cell trait, 27 (9 %) as β-thalassaemia major, 10 (3.33 %) as sickle cell disease, 05...

INTRODUCTION Thalassemia could interfere with some assays for haemoglobin A1c (HbA1c) measurement, therefore, it is useful to be able to screen for thalassemia while measuring HbA1c. We used Capillarys 2 Flex Piercing (Capillarys 2FP) HbA1c programme to simultaneously measure HbA1c and screen for thalassemia. MATERIALS AND METHODS Samples from 498 normal controls and 175 thalassemia patients ...

Many studies have examined pretreatment predictors of immediate posttreatment outcome, but few studies have examined prediction of long-term treatment response to couple therapies. Four groups of predictors (demographic, intrapersonal, communication, and other interpersonal) and 2 moderators (pretreatment severity and type of therapy) were explored as predictors of clinically significant change...