A recently published article by the Scientific Advisory Committee of the Medical Outcomes Trust presents guidelines for selecting and evaluating health status and health-related quality of life measures used in health outcomes research. In their article, they propose a number of validation and performance criteria with which to evaluate such self-report measures. We provide an alternate, yet co...

This paper presents some aspects related to the issues of aggregating economic indicators. Departing from the research of Gh. Paun (1983) we will prove a theorem which states that under certain, natural assumptions, it is impossible to obtain an optimum aggregation. Unlike the original work of Paun, in this paper we are giving a rather simple proof of this theorem.

The validity of the Michaelis-Menten-Briggs-Haldane approximation for single enzyme reactions has recently been improved by the formalism of the total quasi-steady-state approximation. This approach is here extended to fully competitive systems, and a criterion for its validity is provided. We show that it extends the Michaelis-Menten-Briggs-Haldane approximation for such systems for a wide ran...