A Simple and convenient protocol is described for preparation of some new 5-(2’hydroxy-3’,5’-dichlorophenyl)-4-(4’-chlorobenzyl)-2-amino-1,3-thiazole and 5-(2’hydroxy-3’,5’-dichlorophenyl)-4-(4’-chlorobenzyl)-2-aminophenyl-1,3-thiazole, were synthesized by refluxing dibrominated chalcone with thiourea or N-phenyl thiourea in good yields. The newly synthesized titled compounds were screened for ...

Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and an important glycoprotein containing heme group in its structure showing antimicrobial effect on disease causing microorganisms digestive system newborn babies. Thiazoles are simplest members heterocyclic compounds nitrogen sulfur atoms their structure. Many active pharmaceutical substances such as vitamin B1, penicill...

In this study the volatile composition of six samples dark chocolates varying in cocoa roasting time (30.5, 34.5 and 38.5 min) geographical origin (Ecuador Ghana) was characterized by headspace solid-phase microextraction (HS-SPME) followed gas chromatography-mass spectrometry (GC-MS). One hundred twenty-one different compounds were identified using a carboxen/polydimethylsiloxane (CAR-PDMS) fi...

A facile and efficient one-pot three-step process for the synthesis of 5-acetyl-2-imino-4-methylthiazoles via the cyclocondensation of 3-thiocyanatoacetylacetone with various hydrazine or hydrazide derivatives in EtOH has been developed. 3-Thiocyanatoacetylacetone itself has been synthesized as the intermediate from substitution reaction of thiocyanate with 3-chloroacetylacetone. B...