[14C]Artemisinin was taken up by Plasmodium falciparum in culture and concentrated in hemozoin. In vitro, hemin and artemisinin were found to undergo a chemical reaction forming two major products which were isolated by high-performance liquid chromatography (HPLC). The m/z values of the two products were 856 and 871. Thin-layer chromatography (TLC) and HPLC of hemozoin isolated from [14C]artem...

The synthesis of the protected fragment t-butoxycarbonyl-alanine-isoleucine-serine(benzyl)-proline (Pro)-Pro-OH derived from the hormone erythropoietin is described. The analysis of the peptide by high-pressure liquid chromatography (HPLC) and thin-layer chromatography (TLC) yields apparently inconsistent results. Although HPLC consistently indicates the presence of only one component, TLC reve...

In recent years, Salvia divinorum has become a major focus by state legislatures throughout the United States looking to prohibit the sale of the psychoactive plant. After researching testing procedures presented in the literature and those employed by crime laboratories throughout the country, it was decided that thin layer chromatography (TLC) and gas chromatography ⁄mass spectrometry (GC ⁄MS...

A strategy using reversed-phase high-performance liquid chromatography (HPLC), thin layer chromatography (TLC), mass spectrometry (MS), nuclear magnetic resonance (NMR), chemical synthesis, and MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell viability assay to identify allicin as the active anticancer compound in aqueous garlic extract (AGE) is described. Changing the pH...

Different solvent extracts of a red algae, Hypnea flagelliformis,and two brown algae, Cystoseira myrica and Sargassum boveanum, collected from the Persian Gulf coast were subjected to different bioassays including: 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay, antibacterial and antifungal activity by thin layer chromatography (TLC)-bioautography, agar disc diffusion (ADD) ...

Determination of duloxetine by various methods from various matrices is reviewed in this paper. The methods used consist of spectrofluorimetry, ultraviolet (UV) spectroscopy, thin layer chromatography (TLC), and high-performance liquid chromatography (HPLC). These methods were used to determine the amount of duloxetine in bulk drugs, pharmaceutical dosage forms and biological matrix. HPLC with ...

Bajakah wood (Spatholobus Littoralisk Hask) is empirically used by the community to treat stomach pain, diarrhea and even believed be able cancer. Several studies have shown its activity as an antibacterial. The purpose of this study was identify compounds with antibacterial properties using Gas Chromatography Mass Spectroscopy (GCMS). method in research experimental method. plants were obtaine...

One of the components that make up essential oils is phenolic compounds which are widely containedin leaves and bark Balik Angin plant (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz).This study aimed to identify antioxidant activity from thebark plant. The isolation using hydrodistillation compoundswere analyzed gas chromatography-mass spectroscopy (GC-MS). Qualitatively antioxidantacti...

So far sunscreens separation has been achieved primarily by HPLC or TLC on RP-18 or (less frequently) unmodified silica gel as stationary phase. The conditions of chromatographic separation published so far are not suitable for many combinations of UV filters found commonly in cosmetic products. It is therefore reasonable to seek alternative conditions that would make it possible to separate th...