Despite preventive measures, incidence of burns is still one of the important medical problems. Nowadays, it has been suggested that some strains of probiotic bacteria have beneficial effects in treatment of skin injures like skin wounds. The aim of the present study was to evaluate the effects of Lactobacillus acidophilus on second-degree burn wounds in rats. Second-degree burn wounds were ind...

In the heart, thermal injury activates a group of intracellular cysteine proteases known as caspases, which have been suggested to contribute to myocyte inflammation and dyshomeostasis. In this study, Sprague-Dawley rats were given either a third-degree burn over 40% total body surface area plus conventional fluid resuscitation or sham burn injury. Experimental groups included 1) sham burn give...

background: burn injuries and their complications are still considered major threats to society’s health standards. the aim of this study was to describe the epidemiological profile, outcome, and factors associated with children’s burn injuries in shahroud (northeastern iran). methods: this cross-sectional study was performed over a three-year period (2013–2015) on children 12 years and under w...

background: minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. these in-vitro effects proposed minoxidil to be a potential antifibrotic agent. the present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats.  materials and methods: wis...

Background Burn dressings, debridement, surgical incisions, skin grafting and physical therapy are some of painful treatments of burn. According to the studies, distraction techniques have a significant effect on patients’ pain. The present study was designed and conducted to determine the effect of distraction on pain of dressing change in second degree burn in 3-6 year-old children. Materials...

To examine the role of early excision and grafting in the preservation of maximal function of hands with deep dermal burns, we prospectively evaluated 164 burned hands in consecutively admitted patients (mean age, 29 years; mean burn size, 37% of body surface). All hands with burn depths of second degree, deep second degree, or third degree above the level of the tendons and joint capsules were...

Carlson, Deborah L., D. Jean White, David L. Maass, Robin C. Nguyen, Brett Giroir, and Jureta W. Horton. I B overexpression in cardiomyocytes prevents NFB translocation and provides cardioprotection in trauma. Am J Physiol Heart Circ Physiol 284: H804–H814, 2003; 10.1152/ ajpheart.00394.2001.—This study examined the effects of either I B overexpression (transgenic mice) or N-acetylleucinyl-leuc...

Gender-related differences in immune responses to hemorrhage and sepsis have been described. However, most trauma studies continue to limit experimental models to males to avoid the variable responses associated with hormonal fluctuation in proestrus/estrus females. In the present study, male and female (either diestrus or proestrus/estrus) Sprague-Dawley rats (250-325 g) were given a third-deg...

OBJECTIVE To better characterize national genital burns (GBs) characteristics using a large burn registry. We hypothesized that mortality and morbidity will be higher in patients with GBs. METHODS The National Burn Repository, a large North American registry of hospitalized burn patients, was queried for patients with GB. Burn characteristics and mechanism, demographics, mortality, and surgic...