Nanocrystalline alumina powder has been synthesized using solution combustion method. The obtained nanocrystalline alumina powder was used as an efficient catalyst for the synthesis of imidazo[1,2-a]azine derivatives from one-pot three component reaction of benzaldehyde, 2-aminoazine and trimethylsilylcyanide under ultrasonic irradiation and refluxing condition. Reusability of catalyst and shor...

KAl(SO4)2.12H2O is found to efficiently and heterogeneously catalyze the one-pot three-component reaction of 2-(nitromethylene)imidazolidine, malononitrile and aldehydes under mild conditions to afford the corresponding tetrahydroimidazo[1,2-a]pyridine in good yields and short reaction times. Docking  study  of  some  compounds  in  the  active  site  of  α-glucosidase demonstrated  that  these...

The direct three component modified Mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate Betti bases has been carried out over L-proline (20 mol%) with high efficiency under solvent free conditions at 70 OC. Also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of L-proline (20 mol%) in the ethanol under reflux condi...

Nanocrystalline alumina powder has been synthesized using solution combustion method. The obtained nanocrystalline alumina powder was used as an efficient catalyst for the synthesis of imidazo[1,2-a]azine derivatives from one-pot three component reaction of benzaldehyde, 2-aminoazine and trimethylsilylcyanide under ultrasonic irradiation and refluxing condition. Reusability of catalyst and shor...

Sulfonated polystyrene/montmorillonite nanocomposite (OMMT/PS-SO3H) was prepared and used as a novel, efficient and inexpensive heterogeneous acid catalyst in the one-pot reaction three-component Mannich reaction of ketones, aromatic aldehydes and amines under solvent-free conditions. The catalyst was characterized by XRD, SEM, TG, BET and FT-IR techniques. This method has advantages...

The Brønsted acidic ionic liquid ([BMIm]HSO4) catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives at room temperature. The integrity of the ionic liquid remains reasonably unchanged when it is separated from the reaction mixture by water extraction, as it can be recycled several times without any loss of activity in each of the title syntheses. The products a...

In this work, an efficient and green procedure for the synthesis of various substituted 1,5-benzodiazepine derivatives via a one-pot three-component catalytic reaction has been described. The reaction was conducted between o-phenylenediamine, dimedone and aldehyde derivatives in the presence of CuFe2O4 nanoparticles as a magnetic heterogeneous nanocatalyst under ball-milling conditions at room ...

sulfuric acid {[3-(3-silicapropyl)sulfanyl]propyl}ester (saspspe) is employed as a recyclable catalyst for the synthesis of α-amino nitriles. these syntheses were performed via a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide under mild reaction conditions at room temperature. the catalyst could be recycled and reused several times without any loss of effi...

an efficient and direct procedure for the synthesis of benzo[h]-indeno[1,2-b]-quinoline derivatives has been described. the procedure employs a three-component condensation reaction in one-pot using 2h-indene-1, 3-dione, naphthalen-1-amine,and aldehydes in the presence of catalytic amount of l-prolinein aqueous media.

A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...