Huntington disease (HD) is associated with expansions of a CAG trinucleotide repeat in the HD gene. Accurate measurement of a specific CAG repeat sequence in the HD gene in 92 Brazilian controls without HD, 44 Brazilian subjects with clinical findings suggestive of HD and 40 individuals from 6 putative HD families, showed a range from 7 to 33 repeats in normal subjects and 39 to 88 repeats in a...

anniversary of the Brazilian Journal of Cardiovascular Surgery (BJCVS). We asked some collaborators of the Journal to express their sentiments about the interaction of them with the publication, and the importance that it represented in their lives. Was not surprise to have many important manifestations of the colleagues, to show historical facts and personal impressions about the challenge tha...

The temporomandibular joint (TMJ) disc consists mainly of collagen fibers and proteoglycans constrained in the interstices of the collagen fiber mesh. This construction results in a viscoelastic response of the disc to loading and enables the disc to play an important role as a stress absorber during function. The viscoelastic properties depend on the direction (tension, compression, and shear)...

purpose: to report a case who had optic disc duplication, a rare congenital disorder characterized by two well-defined discs in one eye. case report: a 19 months-old child presented with unilateral epiphora in the right eye since birthday. the right eye was smaller than the left eye and mild ptosis was apparent. nasolacrimal duct probing was performed under general anesthesia. the examination r...

We numerically study the long-term evolution of the accretion disc around the neutron star in a coplanar Be/X-ray binary with a short period and a moderate eccentricity. From three dimensional Smoothed Particle Hydrodynamics simulations, we find that the disc evolves through three distinct phases, each characterized by different mass accretion patterns. In the first ”developing phase”, the disc...

Global stationary configurations of both aligned and logarithmic spiral magnetohydrodynamic (MHD) perturbations are constructed analytically within an axisymmetric background of razor-thin scale-free gas disc, which is embedded in an axisymmetric gravitational potential of a dark matter halo and involves an isopedic magnetic field almost vertically threaded through the disc plane. The scale-fre...

The differentiated ectodermal basal disc cells of the freshwater cnidarian Hydra secrete proteinaceous glue to temporarily attach themselves to underwater surfaces. Using transcriptome sequencing and a basal disc-specific RNA-seq combined with in situ hybridisation a highly specific set of candidate adhesive genes was identified. A de novo transcriptome assembly of 55,849 transcripts (>200 bp) ...

Two solutions to design a thin annular disc of variable thickness subject to thermomechanical loading are proposed. It is assumed that the thickness of the disc is everywhere sufficiently small for the stresses to be averaged through the thickness. The state of stress is plane. The initiation of plastic yielding is controlled by Mises yield criterion. The design criterion for one of the solutio...

Temporomandibular disorders embrace a number of clinical conditions that involves the masticatory musculature, temporomandibular joint (TMJ) and associated structures. The most frequent cause of TMJ disorders are disc derangement disorders which involve progressive slipping or displacement of articular disc. Various conservative treatment strategies for disc derangement disorders includes pharm...