MOTIVATION Time course data are often used to study the changes to a biological process after perturbation. Statistical methods have been developed to determine whether such a perturbation induces changes over time, e.g. comparing a perturbed and unperturbed time course dataset to uncover differences. However, existing methods do not provide a principled statistical approach to identify the spe...

Stimuli caused by actions (i.e., effects) are perceived earlier than stimuli not caused by actions. This phenomenon is termed intentional binding (IB) and serves as implicit measure of sense of agency. We investigated the influence of effect delay and temporal predictability on IB, operationalized as the bias to perceive the effect as temporally shifted toward the action. For short delays, IB i...

Statistical challenges arise from modern biomedical studies that produce time course genomic data with ultrahigh dimensions. In a renal cancer study that motivated this paper, the pharmacokinetic measures of a tumor suppressor (CCI-779) and expression levels of 12,625 genes were measured for each of 33 patients at 8 and 16 weeks after the start of treatments, with the goal of identifying predic...

The perception of coarticulated speech as it unfolds over time was investigated by monitoring eye movements of participants as they listened to words with oral vowels or with late or early onset of anticipatory vowel nasalization. When listeners heard [CṼNC] and had visual choices of images of CVNC (e.g., send) and CVC (said) words, they fixated more quickly and more often on the CVNC image whe...

We describe a novel method for tracking the time course of visual identification processes, here applied to the specific case of letter perception. We combine a new behavioral measure of letter identification times with single-letter ERP recordings. Letter identification processes are considered to take place in those time windows in which the behavioral measure and ERPs are correlated. A first...

Studies in change blindness re-enforce the suggestion that veridical, pictorial representations that survive multiple relocations of gaze are unlikely to be generated in the visual system. However, more abstract information may well be extracted and represented by the visual system. In this paper we study the types of information that are retained and the time courses over which these represent...

Does the similarity between two items change over time? Previous studies (Goldstone & Medin, 1994; Gentner & Brem, 1999) have found suggestive results but have relied on interpreting complex interaction effects from “deadline” decision tasks in which the decision making process is not well understood (Luce, 1986). Using a self-paced simple decision task in which the similarity between two items...