BACKGROUND The current, so-called "Millennial" generation of learners is frequently characterized as having deep understanding of, and appreciation for, technology and social connectedness. This generation of learners has also been molded by a unique set of cultural influences that are essential for medical educators to consider in all aspects of their teaching, including curriculum design, stu...

Chromosome ends contain nucleoprotein structures known as telomeres. Damage to chromosome ends during interphase elicits a DNA damage response (DDR) resulting in cell cycle arrest. However, little is known regarding the signaling from damaged chromosome ends (designated here as "TIPs") during mitosis. In the present study, we investigated the consequences of DNA damage induced at a single TIP i...

This position paper proposes the need for researching the use of case teaching method in computing education and subsequently developing a case repository and set of practical tips on how case method can be incorporated into the different computing courses. Keywords—case-based teaching; computing education; case respository; teaching cases

This paper documents predictable time-variation in the real return beta of U.S. Treasury inflation protected securities (TIPS) and in the Sharpe ratios of both indexed and conventional bonds. The conditional mean and volatility of both bonds and their conditional correlation are first estimated from predetermined variables. These estimates are then used to compute conditional real return betas ...

The acquisition of public sector complex systems is time-consuming, very expensive, and rife with uncertainties. The enterprise associated with acquisition is an excellent candidate for transformation—fundamental change to achieve substantially higher levels of value. This paper argues that choosing among alternative transformation initiatives should be based on an enterprise-wide perspective a...

In this paper, edge crack problems under mechanical loads have been analysed using extended finite element method (XFEM) as it has proved to be a competent method for handling problems with discontinuities. The XFEM provides a versatile technique to model discontinuities in the solution domain without re-meshing or conformal mesh. The stress intensity factors (SIF) have been calculated by domai...

You will need: 2 very dry coconuts About ¼ pints of water This gives about oil. Method: Grate coconuts. Some you fingernails and the tips finger get grate off too. Add wat...

TIPS-pentacene is a small-molecule organic semiconductor that widely used in optoelectronic devices. It has been studied intensely owing to its ability undergo singlet fission. In this study, we aim develop further understanding of the coupling between electronic and nuclear degrees freedom (TIPS-Pn). We measured analyzed 2D spectra TIPS-Pn solutions. Using center line slope (CLS) analysis, cha...

Nanoindentation testing of compliant materials has recently attracted substantial attention. However, nanoindentation is not readily applicable to softer materials, as numerous challenges remain to be overcome. One key concern is the significant effect of adhesion between the indenter tip and the sample, leading to larger contact areas and higher contact stiffness for a given applied force rela...