Warty dyskeratoma is an uncommon entity characterized by a solitary keratotic papule or nodule usually located in the head and neck of young adults. The histopathology shows a pattern of acantholytic dyskeratosis. We report a 32-year-old man who presented pain, serous exudation, a distal onycholysis with subungual hyperkeratosis, and roundish erythronychia in the nail plate of his left first to...

In dystrophic epidermolysis bullosa, the genetic defect of anchoring fibrils leads to cleavage beneath the basement membrane and its consequent loss. A 46 year-old female patient presented blisters with a pretibial distribution associated with nail dystrophy. Her two children had hyponychia and anonychia, which affected all toe nails and the thumb, forefinger and middle finger. DNA sequencing i...

Herpes simplex virus (HSV) is a common pathogen that can infect any cutaneous or mucocutaneous site. Although the most common types of primary infections are gingivostomatitis and genital herpes, l infection of the finger is also frequently reported. In 1909 Adamson published the first report of herpetic infections of the hand.2 The term herpetic whitlow was first applied by Stern in his 1959 d...

Onychomycosis is a common progressive fungal infection of the nail bed, matrix, or plate leading to destruction and deformity of the toenails and fingernails. The prevalence of onychomycosis is increasing in the United States, particularly in the growing population of Latino patients. In this study, we evaluated the efficacy and safety of efinaconazole solution 10% in Latino patients with onych...

Onychomycosis, the fungal infection of nail is a common occurrence. The conventional fungi implicated are dermatophytes and Candida species. Non-dermatophytic moulds account for few cases and Chaetomium globosum is an exceptional agent. This characteristically involves the toe nails which are dystrophic and discoloured yellow-brown. Direct microscopy shows brown septate hyphae. Isolate is rapid...

Volume 89, Number 10 www.aafp.org/afp American Family Physician 793 A 19-year-old woman presented with a slowly enlarging, painful nodule under her left great toenail that appeared two years earlier. She had attempted to remove part of the nodule on her own, but it grew back. She did not have a history of trauma to the area, but she noted increased pain when she wore tight or high-heeled shoes....

In the years 1977-1996 103 cases of mycosis caused by Trichophyton tonsurans with lesions in a variety of locations were treated. T. tonsurans was most often cultured from the feet (61.2%), and toe nails (22.3%), although smaller quantities were also obtained from other locations. In 1990, an endemic focus of superficial ringworm of the hairless skin caused by T. tonsurans was observed in 23 vi...

BACKGROUND Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population. OBJECTIVES To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis. METHODS We evaluated 331 patients with suspected clinical toenail onychomycosis affecting at least two toen...

The subungual exostosis is a benign bone tumor on the distal phalanx of a digit, beneath or adjacent to the nail, often bringing in discussion many differential diagnosis. We present a 14-year-old boy with a cutaneous nodular lesion, painful to the easy touch on the latero-internal half of the nail of right big toe with extension in the cutaneous part of this. He suffered many treatments, espec...

Sparfloxacin, a synthetic, second generation, broad spectrum aminodifluoroquinolone antibiotic, has excellent penetration into respiratory tissues and has good activity against Gram-positive, Gram-negative, and atypical bacteria. Although it is indicated for the treatment of adult community-acquired pneumonia and acute exacerbation of chronic bronchitis, its use has been limited by phototoxicit...