Coordination between the Hertwig’s epithelial root sheath (HERS) and apical papilla (AP) is crucial for proper tooth root development. The hedgehog (Hh) signaling pathway and Nfic are both involved in tooth root development; however, their relationship has yet to be elucidated. Here, we establish a timecourse of mouse molar root development by histological staining of sections, and we demonstra...

Aim: Previous studies have demonstrated that orthodontic forces may injure dental pulp tissue via the apical foramen. The purpose of this study was to investigate the expression of various cytokines in pulp tissues of root apex after orthodontic tooth movement and compare the amount of internal root resorption in vital and pulp less rat teeth. Methods: Upper right first molars of 7-week Wistar ...

Introduction. Tooth avulsion in the young permanent dentition is a frequent finding, and its prognosis depends on the treatment of the avulsed tooth before replantation, the extra-alveolar time, the storage medium, and the patient's general health. The present report describes management of an immature avulsed lower central incisor 90 minutes after the accident. Methods. A right lower central i...

INTRODUCTION In patients, the outcomes of teeth with necrotic pulps and open apexes that have been treated with regenerative endodontics have always been evaluated clinically and radiographically. The purpose of this case report is to present the clinical, radiographic, and histological findings of a regenerative procedure using platelet-rich plasma (PRP) 14 months after the procedure. METHOD...

Management of internal root resorption is a challenge to the endodontists. If it is left untreated, it may lead to the destruction of the surrounding dental hard tissues. Despite, routine obturation techniques are often employed without considering the best technique to solve this problem. This study presented a case of internal root resorption and apical periodontitis affecting tooth 12 (FDI) ...

Gemination, a relatively uncommon dental anomaly, is characterized by its peculiar representation as a tooth with a bifid crown and a common root and root canal. It usually occurs in primary dentition. To come across gemination in a supernumerary tooth is a rare phenomenon. The purpose of this paper is to present a unique case of hyperdontia wherein gemination in an impacted supernumerary tooth...

INTRODUCTION We investigated the root canal configuration of maxillary premolars in a Spanish population by using cone-beam computed tomography. METHODS Images of 804 maxillary first and second premolars were obtained from 620 patients who underwent cone-beam computed tomography scanning during preoperative assessment (before implant surgery, orthodontic treatment, dentoalveolar trauma diagno...

Wolf tooth is a common term used to describe the first premolar, a functionless remnant from modern horse’s ancestors. This study was performed to reveal possible relationships between morphometric characteristics of wolf tooth and its clinical importance in animal’s health. A total of 158 wolf teeth were extracted from 83 horses from 1.5 to 15 years of age during a period of one year and divid...