conclusions temperaments can provide a basis to classify psychiatric disorders. psychiatric disorders can be placed in a spectrum based on temperaments. results four groups of temperaments were identified: high active, high flexible; high active, low flexible; low active, low flexible; and low active, high flexible. when temperament deteriorates personality, non-psychotic, and psychotic psychia...

objective: this study was conducted to compare the results of fixed versus flexible gnrh antagonist protocols in controlled ovarian stimulation for intra cytoplasmic sperm injection (icsi) in patients with pcos. materials and methods: a randomized clinical trial was performed on 100 pcos women, who were admitted to a tertiary infertility clinic and were candidate for ivf/icsi. they were divided...

The motor enzyme kinesin makes hundreds of unidirectional 8-nanometer steps without detaching from or freely sliding along the microtubule on which it moves. We investigated the kinesin stepping mechanism by immobilizing a Drosophila kinesin derivative through the carboxyl-terminal end of the neck coiled-coil domain and measuring orientations of microtubules moved by single enzyme molecules at ...

The assembly of RecA onto a torsionally constrained double-stranded DNA molecule was followed in real time using magnetic tweezers. Formation of a RecA-DNA filament on the DNA tether was stalled owing to different physical processes depending on the applied stretching force. For forces up to 3.6 pN, the reaction stalled owing to the formation of positive plectonemes in the remaining DNA molecul...

The V-like dependence of the electrophoretic mobility of small DNA rings on their topological constraint, which has been documented in a recent paper [Zivanovic et al. (1986), J. Mol. Biol., 192, 645-660], has been explored as a tool to measure the helical twist of the torsionally unstressed duplex. The method was applied to single mixed sequence fragments approximately 350 to 1400 base pairs i...

The rotationally resolved spectrum of the electronic origin of methylstyrene has been studied in order to obtain the geometric structure and the barriers to methyl torsion in the electronic ground and excited state. The spectrum has been analyzed using an automated assignment based on the Genetic Algorithm. The geometry is found to be quinoidally distorted upon electronic excitation, what is ty...

Combining linear Zn porphyrin trimers with orthogonally derivatized porphyrin dimers leads rapidly and spontaneously to the formation of monodisperse, torsionally constrained boxes comprising six components and a total of 16 metalloporphyrins. In situ X-ray scattering measurements confirm the formation of monodisperse assemblies of precisely the size expected from model box structures. While si...

Using numerical simulations, we compare properties of knotted DNA molecules that are either torsionally relaxed or supercoiled. We observe that DNA supercoiling tightens knotted portions of DNA molecules and accentuates the difference in curvature between knotted and unknotted regions. The increased curvature of knotted regions is expected to make them preferential substrates of type IIA topois...

Flow visualisation using tracer and particle techniques is well known to be susceptible to fallacious interpretation for unsteady shear flows. Recent experimental observations using these types of techniques have led to the conclusion that even for low Reynolds number flows, the vortex breakdown bubble in a torsionally driven cylinder is not closed and has an inflow/outflow asymmetry at its tai...

In this work, we detail the design, fabrication, and initial modeling of a compact, high-strength series elastic element designed for use in snake robots. The spring achieves its elasticity by torsionally shearing a rubber elastomer that is bonded to two rigid plates, and it is able to achieve mechanical compliance and energy storage that is an order of magnitude greater than traditional spring...