We here analyzed the prevalence of extra-thyroidal malignancies (EM) in 6,386 female patients affected by different thyroid disease (TD). At first, an age-matched analysis of EM in all patients was performed. We then evaluated EM prevalence in four TD diagnostic categories: non-nodular TD (n = 2,159); solitary nodule (n = 905); multinodular TD (n = 2,871); differentiated thyroid cancers (n = 45...

BACKGROUND The aim of this study was to determine the reference values for thyrotropin (TSH), thyroid hormones (total and free thyroxine, T4 and fT4; total and free triiodothyronine, T3 and fT3), thyroglobulin (Tg) and thyroid antibodies (thyroid peroxidase, TPOAb and thyroglobulin antibody, TgAb) in the population of the Republic of Srpska. METHODS A total of 250 euthyroid subjects were enro...

PURPOSE We aimed to compare the ultrasonographic and laboratory parameters of euthyroid patients who have only positive antithyroid autoantibody test results with those of patients with a hypothyroid status of Hashimoto's thyroiditis (HT). MATERIALS AND METHODS Thirty-five patients with newly diagnosed HT, 35 euthyroid patients who have autoantibodies against thyroid peroxidase (TPOAb) and/or...

OBJECTIVE Because of major technical improvements and conscious care about cost effectiveness, limiting the inadequate use of thyroid biological tests appears to be a major issue. DESIGN To (i) estimate the ordering prevalence of each thyroid test, (ii) assess the prevalence of relevant thyroid tests, and (iii) evaluate the impact of expressing justification for tests during a 2-month interve...

OBJECTIVE Vitamin D deficiency is associated with several autoimmune diseases. This study assessed whether vitamin D deficiency is associated with Hashimoto thyroiditis (HT). METHODS Two groups of patients were selected for which serum 25-hydroxyvitamin D (25(OH)D) levels had been measured: (1) a study group of patients diagnosed with HT as indicated by thyroid antibodies, and (2) a healthy c...

Functional deficiency of mannan-binding lectin (MBL) has been associated with adverse pregnancy outcome. Adverse events during pregnancy have also been described in women with autoimmune thyroid diseases (AITD), and thyroid hormones have been shown to influence serum levels of MBL. Therefore, the aim of this study was to analyse the impact of MBL-deficiency on the outcome of pregnancy in relati...

Objective. The main objective of this study is to evaluate the clinical efficacy antithyroid drugs combined with antioxidant supplementation represented by selenium in treatment Graves’ disease. Methods. Relevant randomized controlled trials (RCTs) were searched PubMed, MEDLINE, Embase, Cochrane Library databases, and Chinese Medical Association. search was conducted from time library construct...

Objetivo: Conhecer quais os principais fatores desencadeadores da tireoidite pós-parto durante a gestação. Métodos: Consiste em um estudo secundário, com uma abordagem quantitativa, do tipo revisão bibliográfica integrativa, que foram utilizados Descritores Ciências Saúde (DeCs) inglês “Postpartum Thyroiditis" e "Pregnancy" para busca de trabalhos nas bases dados Biblioteca Virtual (BVS) Medica...

Objective: To compare thyroid hormone profile (T3, T4, TSH, Anti TPOAb, & TBG) among fertile and infertile females. Study Design: Case-control study. Setting: Department of Physiology Gynecology Obstetrics, JPMC Karachi, BMSI. Period: Jan 2018 to 2019. Material Methods: There were 88 participants in the sample, who split into two groups. Infertile group (group A) control B). Non-probability...