BACKGROUND Obesity and osteoporosis, two possibly related conditions, are rapidly expanding health concerns in modern society. Both of them are associated with sedentary life style and nutrition. To investigate the effects of diet-induced obesity and voluntary physical activity we used high resolution micro-computed tomography (μCT) together with peripheral quantitative computed tomography (pQC...

OBJECTIVE To analyze morphological abnormalities of the talus in patients with clubfoot after surgical treatment using the McKay technique. METHOD Lateral standing-position radiographs of the feet of 14 patients with unilateral clubfoot who underwent treatment by means of the doubleincision McKay technique were retrospectively analyzed. All the patients were operated by the same surgeon, with...

PURPOSE This study was performed to evaluate possible variations in maxillary and mandibular bone texture of normal population using the fractal analysis, particles count, and area fraction in intraoral radiographs. MATERIALS AND METHODS Periapical radiographs of patients who had full mouth intraoral radiographs were collected. Regions of interest (100×100 pixels) were located between the tee...

Differentiation of hepatocellular carcinoma (HCC) from metastatic carcinoma in liver may be difficult on fine needle aspiration cytology (FNAC), when both appear as moderate to poorly differentiated tumours. The present study was done to assess clinical, serological, biochemical, radiological and detailed cytomorphological features to distinguish HCC from metastatic carcinoma in FNAC of the liv...

BACKGROUND Transient early-life perturbations in glucocorticoids (GC) are linked with cardiovascular disease risk in later life. Here the impact of early life manipulations of GC on adult heart structure, function and gene expression were assessed. METHODS AND RESULTS Zebrafish embryos were incubated in dexamethasone (Dex) or injected with targeted glucocorticoid receptor (GR) morpholino knoc...

A mutation in LRP5 (low-density lipoprotein receptor-related protein 5) has been shown to increase bone mass and density in humans and animals. Transgenic mice expressing the LRP5 mutation (G171V) demonstrate an increase in bone mass as compared to non-transgenic (NTG) littermates. This study evaluated LRP5 gene and gender-related influences on the structural and biomechanical strength properti...

Aim: The purpose of the present study was to evaluate choice grafting options post apicectomy procedure by various endodontists. Methodology: In descriptive survey, 8 questions were asked from 50 Endodontists, regarding treatment in cases periapical pathologies as well graft material preference after apicoectomy performed. They for usability, economics, long term healing region related with pla...

Juxtacanalicular (JXT) trabecular meshwork and endothelial lining of Schlemm's canal have been cited as the loci of aqueous outflow resistance, both in a normal as well as a glaucomatous eye. In this review, we attempt to understand the currently available surgical modalities in light of the available histopathological evidence, regarding localization of outflow resistance. How to cite this art...

Aims Prediction of trabecular fracture zone is a wide challenge not yet solved. Some in-vitro studies pointed out the importance of local variation of the framework for the global behavior of the whole trabecular structure [1-4]. Researchers agree that the identification of the weakest link in the trabecular framework can lead to the prediction of the fracture zone, first, and of the failure ev...

Trabecular bone structure has an important influence on bone strength, but little is known about its genetic regulation. To elucidate the genetic factor(s) regulating trabecular bone structure, we compared the trabecular bone structures of two genetically remote mouse strains, C57BL/6J and Japanese wild mouse-derived MSM/Ms. Phenotyping by X-ray micro-CT revealed that MSM/Ms has structurally mo...