a b s t r a c tthe applications of neurophysiological therapy techniques range far and few in the realm of modern day medicine. however, the concept of electromagnetic stimulation, the basis for many noninvasive brain stimulation (nibs) techniques today, has been of interest to the scientific community since the late nineteenth century. recently, transcranial direct current stimulation (tdcs) a...

During the past 20 years, non-invasive brain stimulation has become an emerging field in clinical neuroscience due to its capability to transiently modulate corticospinal excitability, motor and cognitive functions. Whereas transcranial magnetic stimulation has been used extensively since more than two decades ago as a potential "neuromodulator", transcranial current stimulation (tCS) has more ...

Abstract Among other electrophysiological biomarkers, power reduction in the alpha frequency band (8-12 Hz) is characteristic of Alzheimer’s Disease (AD). Restoring this could help improve performance related functional networks and cognitive state AD patients. Transcranial alternate current stimulation (tACS) stands as a promising tool regard, given its capacity to entrain neural activity at p...

Non-invasive electrical brain stimulation (NEBS) is used to modulate brain function and behavior, both for research and clinical purposes. In particular, NEBS can be applied transcranially either as direct current stimulation (tDCS) or alternating current stimulation (tACS). These stimulation types exert time-, dose- and in the case of tDCS polarity-specific effects on motor function and skill ...

It has been 211 years since C. Grapengiesser first published a book entitled Galvanism to Cure Some Diseases (original title: Galvanismus zur Heilung einiger Krankheiten) describing the successful use of galvanic currents in treating several patients with pain and strokes. A comparatively short time of slightly more than a decade has passed since tDCS with weak currents in the range of 1 to 2 m...

Beta and gamma oscillations are the dominant oscillatory activity in the human motor cortex (M1). However, their physiological basis and precise functional significance remain poorly understood. Here, we used transcranial magnetic stimulation (TMS) to examine the physiological basis and behavioral relevance of driving beta and gamma oscillatory activity in the human M1 using transcranial altern...

Transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) are noninvasive neuromodulatory techniques that deliver low-intensity currents facilitating or inhibiting spontaneous neuronal activity. These techniques have a number of advantages that have been applied in clinical settings; in particular, tDCS/tACS dose in principle is easily customized by ...

Transcranial alternating current stimulation (tACS) is a re-emergent neuromodulation technique that consists in the external application of oscillating electrical currents that induces changes in cortical excitability. We present the case of a 16-year-old female with pharmaco-resistant juvenile myoclonic epilepsy to 3 antiepileptic's drugs characterized by 4 myoclonic and 20 absence seizures mo...

Objective: We investigated changes in cortico–subcortical spatiotemporal dynamics to explore the treatment mechanisms of transcranial alternating current stimulation (tACS) patients with Parkinson’s disease (PD). Methods: Resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 20 PD and normal controls (NC). Each patient received successive multidisciplinary inten...

Noninvasive alternating current stimulation can induce vision restoration in patients with chronic optic nerve damage and results in electroencephalogram (EEG) aftereffects. To better understand the mechanisms of action, we studied such EEG "aftereffects" of transcorneal alternating current stimulation (tACS) at the chronic posttraumatic state in rats. EEG baseline was recorded from visual cort...