Single crystals of Li(6)CuB(4)O(10) have been synthesized, and its crystal structure has been determined. Li(6)CuB(4)O(10) crystallizes in the non-centrosymmetric triclinic space group P1 (No. 1). The structure consists of isolated [CuB(4)O(10)](6)(-) polyanions that are bridged by six LiO(4) tetrahedra. Li(6)CuB(4)O(10) is a congruently melting compound. It produces SHG intensity similar to th...

Interest in the biologic role of trace elements prompted an investigation of their renal excretion. Preliminary qualitative analysis revealed that except for cobalt the entire first transition series of metals, namely, titanium, vanadium, chromium, manganese, iron, nickel and copper, were detectable in most human urines. In addition the heavier transition metals, molybdenum and silver, as well ...

Inhibition of antibacterial activity of polymorphonuclear leukocytic lysosomal cationic proteins by a polyanion, heparin, can be reversed by addition of the basic nuclear protein, clupeine.

An overview is presented of the methodology and computations of nuclear shielding and spin–spin coupling constants of transition metal complexes. The presented material also includes an outline of relativistic approaches and their applications to heavy transition metals.

A polymer-based gene delivery system, denoted as “DNA/polycation/polyanion”, is designed based on the concept of polyelectrolyte multilayer fabrication by the layer-by-layer polyelectrolyte self-assembly technology. The comparisons of the physicochemical properties between ‘core’ DNA/branched polyethylenimine (PEI) and DNA/chitosan complexes suggest that DNA/PEI complexes form as colloidally st...

To determine the regulatory mechanism for human tyrosine hydroxylase, we examined modulations of the activity of the enzyme from human pheochromocytoma by cyclic AMP-dependent protein kinase, calmodulin-dependent protein kinase II and polyanion. The most remarkable activation was observed when the enzyme was assayed at physiological pH (pH 7) after being subjected to phosphorylation by cyclic A...

Quantification of oversulfated chondroitin sulfate (OSCS) in biomedical heparin preparations is achieved using a recently described potentiometric polyanion sensor-based approach operated in a kinetic mode of analysis. This is accomplished by adjusting the concentration of the test sample to a range where the OSCS level is low enough for the sensor not to achieve a full and rapid equilibrium ph...

Spintronic terahertz (THz) emitters based on the inverse spin Hall effect in ferromagnetic/heavy metal (FM/HM) heterostructures have become important sources for THz pulse generation. The design, materials, and control of these interfaces at nanometer level vital to engineer their emission properties. In this work, we present studies optimization such structures through a multi-pronged approach...

It is well established that the gp120 V3 loop of T-cell-line-adapted human immunodeficiency virus type 1 (HIV-1) binds both cell-associated and soluble polyanions. Virus infectivity is increased by interactions between HIV-1 and heparan sulfate proteoglycans on some cell types, and soluble polyanions such as heparin and dextran sulfate neutralize HIV-1 in vitro. However, the analysis of gp120-p...