small cell carcinoma of the urinary bladder (sccub) is an extremely rare bladder malignancy characterized by an aggressive clinical behavior. so, it is important to diagnose this high grade disease by urinary cytology. we report a case of sccub in an old man with chronic lymphocytic leukemia (cll) in remission, while bladder tumor was diagnosed by cytology. with this article, we aimed to review...

conclusions nbi cystoscopy improved the detection rate. although false positives were more common with nbi, this was not statistically significant. nbi found additional aggressive tumors, which underscores the impact of detection in eortc recurrence risk scoring. results fifty patients, aged 63.86 ± 10.05 years, were enrolled. the overall detection rate was 98.9% for nbi vs. 89.4% for wli (p = ...

Bladder cancer is the second most common cancer in the urinary tract and the most frequent histological type is transitional cell carcinoma (TCC). Approximately 70% of these cancers are superficial (no evidence of muscle invasion) in situ (Tis), Ta and T1 carcinomas. The biological behavior of these tumors varies from slight recurrence tendency to a high degree of recurrence and progression. Al...

Carcinoma of the bladder is the seventh most common cancer worldwide [1]. It comprises 3.2% of all cancers, with an estimated 260 000 new cases each year in men and 76 000 in women. The highest incidence rates in males and females occur in Western Europe, North America and Australia. The UK annual incidence is over 10 000 new cases, with a male:female ratio of 5 : 2 [2–5]. Urothelial carcinoma ...

Intravesical adjuvant chemotherapy and neoadjuvant chemotherapy has been respectively administered for superficial transitional cell carcinoma (TCC) of urinary bladder and advanced TCC for years. However, the therapeutic efficacy is limited. Recently, overexpression of aldo-keto reductase (AKR) in lung, esophageal, uterine cervical and ovarian cancers was shown to be closely associated with dis...

Clear cell variants of transitional cell carcinomas (TCC) of the bladder are extremely rare tumors. Only 6 cases have been reported until now. We report of a 67 year old man who presented with fast growing tumor disease. While initial diagnosis showed localized bladder tumor, final histopathology revealed pT4, G3, L1 urothelial carcinoma with clear cell differentiation. No more than 14 weeks af...

The clear cell variant urothelial carcinoma of urinary bladder is very rare and unusual neoplasm defined histologically by clear cell pattern and glycogen-rich cytoplasm. Our case of clear cell carcinoma was diagnosed with immunohistochemistry stain. A 72-year-old man, presented with painless macroscopic hematuria in November 2007. Evaluation revealed papillary tumor in urinary bladder. A trans...

OBJECTIVE To investigate the different emerging trends in the features of bladder cancer along 17 years. PATIENTS AND METHODS During a 17-year period (1988- 2004), 5071 epithelial bladder cancer patients underwent radical cystectomy at the National Cancer Institute (NCI), Cairo University, Egypt. The time was divided into 3 time periods to detect changes of the clinicopathologic features of p...