This study was undertaken to investigate the influence of static magnetic field (SMF) on bone marrow cellular density (BMCD) variation proportionally trabeculae. Female albino Wistar rats exposed with 2.4 ± 0.2 millitesla for 1–4 weeks duration continuously versus 1 h, 2 6 and 8 h/day. Trephine biopsy femurs examined under optical microscope. Data analyzed ImageJ software. Results showed...

Aims. To study the etiology, diagnostic features, and clinical significance of myelonecrosis. Methods. A retrospective review of all trephine biopsies done over 12 years (January 2000 to December 2012) in Department of pathology was done and all trephine biopsies showing MN were identified and studied. Results. Twenty-five cases accounting for 0.4% were identified. Fever and generalized weaknes...

Chronic myeloproliferative disorders (CMPD) are traditionally diagnosed using criteria based on clinical parameters. A framework for an alternative, trephine bone marrow histology-based approach, was provided by the Hanover group of hematopathologist (the "Hanover classification"). The present study describes a single institution experience with the Philadelphia-BCR/ABL negative CMPD diagnosed ...

A 45-year-old woman underwent a bone marrow biopsy for evaluation of persistent, severe transfusion-dependent normocytic anaemia, beginning approximately two months following initiation olaparib and atezolizumab therapy metastatic BRCA1-mutated breast carcinoma. The anaemia had not improved despite discontinuation three months. blood count on the day showed: haemoglobin concentration 82 g/l (po...